Hipotiroid Kongenital dan Hypertrophic Pyloric Stenosis: Pemantauan Selama 3 Bulan

Lanny Christine Gultom, Valensia Vivian The

Abstract

Angka kejadian hipotiroid kongenital (HK) berkisar 1 : 2000-4000 bayi. Deteksi dan tata laksana dini diperlukan agar fungsi neurologi dan perkembangan pasien optimal. Salah satu penyebab muntah berulang pada bayi adalah hypertrophic pyloric stenosis (HPS). Deteksi dan tata
laksana HPS penting karena HPS dapat menyebabkan gagal tumbuh hingga gizi buruk yang berdampak pada IQ. Kasus: Bayi usia 2 bulan tanpa skrining hipotiroid kongenital, masuk ke rumah sakit dengan gejala khas hipotiroid kongenital, yaitu ubun-ubun terbuka, wajah tampak kasar,
makroglosia, kulit kering dan dingin, gagal tumbuh, dan hernia umbilikalis. Selain gejala HK, bayi juga memiliki keluhan muntah berulang yang kemudian didiagnosis HPS. Terapi medikamentosa yang tepat dengan levothyroxine, tindakan pembedahan, dan nutrisi yang adekuat harus
diberikan agar tumbuh kembang optimal.

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References

Dayal D, Prasad R. Congenital hypothyroidism: Current perspectives. Research and Reports in Endocrine Disorders. 2015;5:91-102.

Zung A, Radi A, Almanshanu S. The natural history of congenital hypothyroidism with delayed TSH elevation in neonatal intensive care newborns. Clin Endocrinol. 2020;92:443-9.

Pulungan AB, Soesanti F, Utari A, Pritayati N, Julia M, Annisa D, et al. Preliminary study of newborn screening for congenital hypothyroidism and congenital adrenal hyperplasia in Indonesia. eJKI. 2020;8(2):98-103.

Chen CY, Lee KT, Lee CTC, Lai WT, Huang YB. Epidemiology and clinical characteristics of congenital hypothyroidism in an Asian population: A nationwide populationbased study. J Epidemiol. 2013;23(2):85-94.

Bongers-Schokking J, Resing WCM, Oostdijk W, de Rijke YB, de Muinck Keizer-Schrama SMPF. Relation between early over- and undertreatment and behavioural problems in preadolescent children with congenital hypothyroidism. Hormone Res Paediatr. 2018;90:247-56.

Galea R, Said E. Infantile hypertrophic pyloric stenosis: An epidemiological review. Neonatal Netw. 2018;37(4):197-204.

Pyloric stenosis: An enigma more than a century arter the first successful treatment. Pediatr Surg Internat. 2017;34:21-7.

Hirano T, Jogamoto M, Tamura K. Association of congenital hypothyroidism with congenital hypertrophic pyloric stenosis. Acta Paediatr Jpn. 1988;30(3):371-2.

Peters C, van Trotsenburg ASP, Schoenmakers N. Diagnosis of endocrine disease: Congenital hypothyroidism: Update and perspectives. Eur J Endocrinol. 2018;179(6):297-317.

Yati NP, Utari A, Rustama DS, Soenggoro EP, Marzuki ANS, Pulungan AB, et al. Diagnosis dan tata laksana hipotiroid kongenital. Jakarta: Badan Penerbit Ikatan Dokter Anak Indonesia; 2017 .pp.1-2.

Pulungan AB, Oldenkamp ME, van Trotsenburg ASP, Windarti W, Gunardi H. Effect of delayed diagnosis and treatment of congenital hypothyroidism on intelligence and quality of life: An observational study. Med J Indon. 2019;28(4):396-401.

Wassner AJ, Brown RS. Congenital hypothyroidism recent advances. Curr Opin Endocrinol, Diabetes and Obesity. 2015;22(5):407-12.

Ahmad N, Asra I, Al Saedi SA. Congenital hypothyroidism: Screening, diagnosis, management, and outcome. J Clin Neonatol. 2017;6:64-70.

Rastogi MV, LaFranchi SH. Congenital hypothyroidism. Orphanet J Rare Dis. 2010;5:17.

Nili S, Ghaderi E, Ghotbi N, Baneh FV. Comparison of IQ between patients with treated congenital hypothyroidism and healthy children in the Kurdish population – a historical cohort. Acta Endocrinol. 2015;11(3):299-305.

Direktorat Kesehatan Keluarga Kementerian Kesehatan Republik Indonesia. Buku dan pedoman [Internet]. [cited 2021 Februari 6]. Available from: https://kesga.kemkes.go.id/bukupedoman

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