Socio-demographic Profiles of Cervical Cancer Patients at Cipto Mangunkusumo Hospital - 2009-2019 and Its Association with Cancer Stages at Diagnosis

Fitriyadi Kusuma, Kemal Akbar Suryoadji, Michael Adrian, Tofan Widya Utami, Hariyono Winarto, Tricia Dewi Anggraeni, Kartiwa Hadi Nuryanto, Muhammad Haekal

Abstract

Objective: To determine the socio-demographic profile of cervical cancer patients at Cipto Mangunkusumo Hospital in 2009-2019 based on educational level, parity, age, residence, and employment status and their relationship to cervical cancer stage at diagnosis. Methods: Comparative analytical study was conducted retrospectively based on medical records in Cipto Mangunkusumo Hospital. The selection was based on data completeness: cervical cancer stages, sociodemographic profiles consisting of education level, parity, age, Java or non-Java Island resident, and occupation. Multivariate analysis calculated the association between socio-demographic factors and cervical cancer stages. Data were analyzed using SPSS v.22.0 and Microsoft Excel. Results: This study included 4,584 patients with complete data. Only 19.3% patients were in the early stage, 63.3% had less than three parities, 82.8% of patients had formal primary school education or less, 80.9% patients were aged 18-65 years, 88.3% patients resided in Java Island, and 80.5% didn’t have the occupation. There was a significant association (p <0.05) between cervical cancer stage and educational level (aOR= 0.86; 95% CI= 0.78-0.94) and age (aOR= 1.46; 95% CI= 1.18-1.40). There is no significant association (p >0.05) between cervical cancer stage and parity, residence, and employment status. Conclusion: Low education and old age (> 65-year-old) were associated with the advanced stage of cervical cancer at diagnosis.

 

Tujuan: Mengetahui profil sosiodemografi pasien kanker serviks di Rumah Sakit Cipto Mangunkusumo tahun 2009-2019 berdasarkan tingkat pendidikan, jumlah paritas, usia, status kependudukan, pekerjaan, serta hubungannya terhadap stadium kanker serviks saat diagnosis. Metode: Penelitian analitik komparatif retrospektif berdasarkan data rekam medis Rumah Sakit Cipto Mangunkusumo. Pemilihan sesuai kelengkapan data: stadium kanker serviks, profil status sosiodemografi yang terdiri atas tingkat pendidikan, paritas, usia, penduduk pulau Jawa atau non-Jawa, dan status pekerjaan. Hubungan antar variabel dianalisis multivariat untuk
mencari hubungan berbagai faktor sosiodemografi terhadap stadium kanker serviks. Analisis data menggunakan program SPSS versi 22.0 dan Microsoft Excel.
Hasil: Terdapat 4.584 pasien kanker serviks yang memenuhi kriteria inklusi. Sebanyak 19,3% pasien dengan stadium awal. Selanjutnya 82,8% pasien memiliki pendidikan formal sekolah dasar atau kurang, 63,3% pasien memiliki jumlah paritas kurang dari tiga, 80,9% pasien berusia antara 18-65 tahun, 88,3% pasien berdomisili di pulau Jawa, dan 80,5% tidak bekerja. Didapatkan asosiasi bermakna (p<0,05) antara stadium kanker serviks dan tingkat pendidikan (aOR = 0,86; 95% CI= 0,78-0,94) dan usia (aOR= 1,46; 95% CI= 1,18-1,40). Tidak ditemukan asosiasi bermakna (p>0,05) antara stadium kanker serviks dengan paritas, domisili
kependudukan, dan status pekerjaan. Simpulan: Tingkat pendidikan rendah dan usia lanjut (>65 tahun) berasosiasi dengan stadium lanjut kanker serviks saat diagnosis. 

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References

Manini I, Montomoli E. Epidemiology and prevention of human papillomavirus. Ann Ig. 2018;30(4 Suppl 1):28-32.

Kementerian Kesehatan Republik Indonesia. Riset Kesehatan Dasar 2018 [Internet]. 2018. Available from: https://kesmas.kemkes.go.id/assets/upload/dir_519d41d8cd98f00/files/Hasil-riskesdas-2018_1274.pdf

PDQ Adult Treatment Editorial Board. Cervical cancer treatment (PDQ®): Patient version. 2020 May 13. In: PDQ cancer information summaries. Bethesda (MD): National Cancer Institute (US); 2002.

Nuranna L, Fahrudin A. Survival rate of cervical cancer in national referral hospital in 2012 - 2014. Acta Med Indones. 2019;51(2):145-50.

Thomson C, Forman D. Cancer survival in England and the influence of early diagnosis: What can we learn from recent EUROCARE results and quest. Brit J Cancer. 2009;101:102-9.

Gyenwali D, Pariyar J, Onta SR. Factors associated with late diagnosis of cervical cancer in Nepal. Asian Pac J Cancer Prev. 2013;14(7):4373-7.

Petignat P, Roy M. Diagnosis and management of cervical cancer. BMJ. 2007;335(7623):765-8.

Macleod U, Mitchell ED, Burgess C, Macdonald S, Ramirez AJ. Risk factors for delayed presentation and referral of symptomatic cancer: Evidence for common cancers. Br J Cancer. 2009;101(Suppl 2):92-101.

Hamoonga TE, Likwa RN, Musonda P, Michelo C. Higher educational attainment associated with reduced likelihood of abnormal cervical lesions among Zambian women - A cross sectional study. BMC Cancer. 2017;17(1):681.

Tanturovski D, Zafirova E, Stojovski M, Basheska N, Jovanovska V. Impact of socio-demographic factors on the delayed diagnosis and advanced stage presentation of patients with invasive cervical cancer in Macedonia. Pril (Makedon Akad Nauk Umet Odd Med Nauki). 2013;34(3):71-8. PMID: 24566017.

Liu T, Li S, Ratcliffe J, Chen G. Assessing knowledge and attitudes towards cervical cancer screening among rural women in Eastern China. Int J Environ Res Public Health. 2017;14(9):967.

Mirowsky J, Ross CE. Education, social status, and health. New York: Aldine de Gruyter; 2003

Cutler DM, Lleras-Muney A. Understanding differences in health behaviors by education. J Health Econ. 2010;29(1):1-28.

Hidayat E, Hasibuan DHS, Fitriyati Y. Hubungan kejadian kanker serviks dengan jumlah paritas di RSUD dr. Moewardi tahun 2013. J Kedokt Kes Indones. 2014;6(3):128-36.

Yost S, Hoekstra A. Cervical cancer in women over 65: An analysis of screening. Gynecol Oncol Rep. 2018;25:48-51.

Brun JL, Stoven-Camou D, Trouette R, Lopez M, Chene G, Hocké C. Survival and prognosis of women with invasive cervical cancer according to age. Gynecol Oncol. 2003;91(2):395-401.

Ioka A, Tsukuma H, Ajiki W, Oshima A. Influence of age on cervical cancer survival in Japan. Jpn J Clin Oncol. 2005;35(8):464-9.

Chandrawati R. Faktor risiko yang berpengaruh dengan kejadian kanker serviks di RSUD dr. H. Abdul Moeloek Provinsi Lampung. J Kes. 2016;7(2):282-7.

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