Cermin Dunia Kedokteran https://cdkjournal.com/index.php/cdk <ol> <li><strong>Journal Title: </strong><a title="Cermin Dunia Kedokteran" href="https://cdkjournal.com/">Cermin Dunia Kedokteran</a></li> <li><strong>Initials: </strong>CDK</li> <li><strong>Frequency: </strong>12/ year</li> <li><strong>Online ISSN: </strong>2503-2720</li> <li><strong>Print ISSN: </strong>0125-913X</li> <li><strong>TD-PSE (Kominfo):</strong> 003119.02/DJAI.PSE/07/2022</li> <li><strong>DOI in Crossref: </strong>10.55175</li> <li><strong>Editor in Chief: </strong>Dr. dr. Budi Riyanto W., SpN</li> <li><strong>Publisher: </strong>PT Kalbe Farma Tbk.</li> <li><strong>Accreditation Number</strong>: <a href="https://cdkjournal.com/index.php/cdk/accreditation" target="_blank" rel="noopener">No. 152/E/KPT/2023</a><strong> (<a href="https://sinta.kemdikbud.go.id/journals?q=25032720" target="_blank" rel="noopener">SINTA 4</a>) </strong>Periode Akreditasi: Volume 48 Nomor 6 Tahun 2021 sampai Volume 53 Nomor 5 Tahun 2026 </li> </ol> en-US cdkjurnal@gmail.com (Dita Arccinirmala) cdk@kalbe.co.id (Dodi Sumarna) Mon, 05 Feb 2024 17:59:26 +0700 OJS 3.3.0.13 http://blogs.law.harvard.edu/tech/rss 60 Profil Penyakit Kulit Penduduk Perkampungan Terapung Kepulauan Tihi-tihi dan Selangan, Bontang, Kalimantan Timur, Indonesia https://cdkjournal.com/index.php/cdk/article/view/872 <p><strong>Introduction:</strong> Tihi-tihi and Selangan Islands, floating village areas in Bontang, East Kalimantan, are remote areas in Indonesia, which can only be accessed by sea route. The research was conducted to describe skin diseases in those islands. <strong>Method:</strong> Retrospective observational cross-sectional and descriptive analysis study on floating communities in Tihi-tihi and Selangan Island, Bontang Lestari Village, South Bontang District, Bontang City, East Kalimantan, Indonesia. <strong>Results:</strong> The study was conducted on 95 subjects, mostly female (53%), and the largest age group was 26-45 years (29%), followed by the 5-11 years group (24%). Skin infection diseases (58.96%) were dominated by scabies (67.9% of the skin infection disease group). The second highest was allergic contact dermatitis (41%) from the non-infection group. There is an association between age and disease group (p&lt;0.05), with an odds ratio of 3.164. <strong>Conclusion:</strong> Skin diseases in Tihi-tihi and Selangan Islands are dominated by scabies, followed by allergic contact dermatitis. The pediatric age group is at a three-fold greater risk of developing skin infections than non-infection skin diseases.</p> Fenny Leets Santoso, Anis Irawan Anwar, Farida Tabri, Safruddin Amin, Anni Adriani, Idrianti Idrus, Andi Anwar Arsyad Copyright (c) 2024 Fenny Leets Santoso, Anis Irawan Anwar, Farida Tabri, Safruddin Amin, Anni Adriani, Idrianti Idrus, Andi Anwar Arsyad https://creativecommons.org/licenses/by-nc/4.0 https://cdkjournal.com/index.php/cdk/article/view/872 Thu, 01 Feb 2024 00:00:00 +0700 Komplikasi Sindrom Stevens-Johnson (SSJ) dan Nekrolisis Epidermal Toksik (NET) https://cdkjournal.com/index.php/cdk/article/view/876 <p>Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are life-threatening mucocutaneous reactions with severe skin involvement; may affect many internal organ systems with significant psychosocial complications. Several studies have documented physical complications associated with Stevens-Johnson syndrome and toxic epidermal necrolysis (TEN). SJS/TEN patients require multidisciplinary care to deal with psychological complications and reduced quality of life.</p> Aribowo I Kadek, Angel Benny Wisan Copyright (c) 2024 Aribowo I Kadek https://creativecommons.org/licenses/by-nc/4.0 https://cdkjournal.com/index.php/cdk/article/view/876 Thu, 01 Feb 2024 00:00:00 +0700 Terapi Non-Invasive Continuous Positive Airway Pressure (CPAP) Ventilation pada Keracunan Gas Karbon Monoksida https://cdkjournal.com/index.php/cdk/article/view/1022 <p>Carbon monoxide (CO) poisoning is one of the leading environmental emergencies with high mortality and morbidity. The brain and heart are especially at-risk organs of being affected. Clinical manifestations may closely mimic various nonspecific viral illnesses. Diagnosis is made based on of clinical symptoms, patient history, and the location’s circumstances. Current therapy recommendations for CO poisoning are 100% normobaric oxygen (NBO) or hyperbaric oxygen (HBO). Non-invasive ventilation CPAP (continuous positive airway pressure) method is effective as a therapy for CO poisoning in the emergency room because it can provide tissue oxygenation and eliminate CO quickly.</p> Dedy Kristofer Simangunsong, Septo Sulistio, Eirene Simbolon, Erwin Kristianto Simangunsong Copyright (c) 2024 Dedy Kristofer Simangunsong, Septo Sulistio, Eirene Simbolon, Erwin Kristianto Simangunsong https://creativecommons.org/licenses/by-nc/4.0 https://cdkjournal.com/index.php/cdk/article/view/1022 Thu, 01 Feb 2024 00:00:00 +0700 Tinea Inkognito – Diagnosis dan Tata Laksana https://cdkjournal.com/index.php/cdk/article/view/933 <p>Misuses of high potency steroids which are easily accessible without doctor’s prescription and without any fungal examination, may cause tinea incognito. The term tinea incognito refers to dermatophytoses that have lost their classic clinical appearance; it may lead to misdiagnosis. Tinea incognito may imitate other dermatological diagnoses with polymorphic manifestations, including well-circumscribed round or oval lesion, vesicles and scales. Treatment requires cessation of all steroid use and effective antifungal treatment. Alvina Ulfah Rusmayuni, Limyanti Dwi</p> Alvina Rusmayuni, Limyanti Dwi Vicaria Copyright (c) 2024 Alvina Rusmayuni https://creativecommons.org/licenses/by-nc/4.0 https://cdkjournal.com/index.php/cdk/article/view/933 Thu, 01 Feb 2024 00:00:00 +0700 Severe Malaria with Multiple Complications https://cdkjournal.com/index.php/cdk/article/view/865 <p><strong>Background:</strong> Malaria is still a major global health concern with a high mortality rate. The clinical spectrums of malaria range from mild to life-threatening. <strong>Case:</strong> A 25-year-old male with weakness, fever, and anuria. Physical examination showed febris, jaundice, and abdominal tenderness at the right upper quadrant. Laboratory findings revealed <em>Plasmodium falciparum</em> hyperparasitemia with increased total bilirubin and creatinine levels. Diagnosis of severe falciparum malaria with multiple complications (cholecystitis, acute kidney injury, and anemia) was established. Intravenous antimalarial and antibiotics were administered along with hemodialysis. The patient was discharged after 11 days of treatment with the improvement of clinical status and laboratory parameters. <strong>Conclusion:</strong> A comprehensive approach to the diagnosis of malaria is necessary to detect complications and appropriate management.</p> Andrio Palayukan, Nisan Soeheri Copyright (c) 2024 Andrio Palayukan, Nisan Soeheri https://creativecommons.org/licenses/by-nc/4.0 https://cdkjournal.com/index.php/cdk/article/view/865 Thu, 01 Feb 2024 00:00:00 +0700 Severe Tropical Malaria with Acute Kidney Injury: A Case in a Remote Area https://cdkjournal.com/index.php/cdk/article/view/898 <p><strong>Background:</strong> Malaria remains a major health problem in Indonesia; <em>P. falciparum</em> is responsible for the majority of severe cases and malaria-related deaths. This report presents a case of severe tropical malaria complicated with acute kidney injury treated in a remote area with limited resources. <strong>Case: A</strong> 25-year-old male with a 9-day history of fever presented to the emergency department with severe headache, nausea, jaundice, abdominal pain, and hemoglobinuria. Microscopic examination of the blood revealed <em>P. falciparum</em> parasites. Laboratory results also showed anemia and thrombocytopenia, bilirubinuria, proteinuria, elevated liver enzymes, and pre-renal azotemia. The patient received antimalarial treatment (dihidroartemisinin/piperaquine once daily for 3 days and a single dose of primaquine) and supportive therapy. He was discharged in a stable condition on the fifth day of hospitalization. <strong>Conclusion:</strong> Early detection and management is crucial for the patient’s prognosis.</p> Prayoga Adinawer Sirait Copyright (c) 2024 Prayoga Adinawer Sirait https://creativecommons.org/licenses/by-nc/4.0 https://cdkjournal.com/index.php/cdk/article/view/898 Thu, 01 Feb 2024 00:00:00 +0700 Peran Lumbrokinase pada Tata Laksana Stroke Iskemik https://cdkjournal.com/index.php/cdk/article/view/1021 <p>Stroke is a major cause of disability and cognitive impairment, accounting for 5.2% deaths worldwide. Antiplatelets and anticoagulants have been widely used as prevention of recurrent stroke. Recently, lumbrokinase has been used in stroke and other cardiovascular patients, but further research is needed.</p> Marcellinus Michael Leonard Mardiono Copyright (c) 2024 Marcellinus Michael Leonard Mardiono https://creativecommons.org/licenses/by-nc/4.0 https://cdkjournal.com/index.php/cdk/article/view/1021 Thu, 01 Feb 2024 00:00:00 +0700 Efektivitas Citicoline sebagai Terapi Gangguan Kognitif pada Stroke Iskemik Akut https://cdkjournal.com/index.php/cdk/article/view/971 <p><strong>Background:</strong> Cognitive impairment in acute ischemic stroke is associated with disability, poor functional outcome, and mortality, hence requires effective management. Citicoline is one of pharmacotherapy for central nervous system disorders. This study aims to evaluate current evidence of the effectiveness of citicoline for cognitive impairment in acute ischemic stroke. <strong>Methods:</strong> Systematic review and meta-analysis on randomized controlled trials searched in PubMed, Cochrane, and Google Scholar databases. Screening was done on 518 articles according to inclusion and exclusion criteria, 3 articles were qualified for review. <strong>Results:</strong> Cano-Cuenca, et al, (2015) found that citicoline was associated with a mini-mental state examination (MMSE) score of &gt;25 at 12 weeks. Pinzon &amp; Asanyi (2018) found that the use of citicoline can prevent cognitive impairment at 6 and 12 months, especially in attention and temporal orientation. Bonvicini, et al, (2022) found that citicoline is associated with good cognitive outcomes as measured with global cognitive impairment. <strong>Conclusion:</strong> Citicoline is effective as a therapy for cognitive impairment in acute ischemic stroke.</p> Lothar Matheus Manson Vanende Silalahi, Pradita Sri Mitasari Copyright (c) 2024 Lothar Matheus Manson Vanende Silalahi, Pradita Sri Mitasari https://creativecommons.org/licenses/by-nc/4.0 https://cdkjournal.com/index.php/cdk/article/view/971 Thu, 01 Feb 2024 00:00:00 +0700 Efektivitas Tetes Mata Citicoline terhadap Perbaikan Lapang Pandang dan Ketebalan Lapisan Serabut Saraf Retina pada Glaukoma Primer Sudut Terbuka https://cdkjournal.com/index.php/cdk/article/view/1046 <p>Primary open-angle glaucoma (POAG) is the second leading cause of irreversible blindness worldwide with increasing prevalence. Oral citicoline has been shown to have a role in glaucoma; however, studies regarding citicoline eye drops for glaucoma are still limited. This is a critical appraisal of the literature on the effectiveness of citicoline in improving the mean deviation (MD) of the visual field and thickness of the retinal nerve fiber layer (RNFL) in POAG. A literature search was done on 4 databases: PubMed, Cochrane, Embase, and Scopus. From the 165 studies initially identified, 3 studies were qualified for critical review. Rossetti demonstrated significant MD (p=0.02) and RNFL (p=0.04) differences after 3 years of citicoline eye drops compared to placebo. Mirachtsis showed that after citicoline administration for 3 months there was a significant difference in RNFL (p=0.029), but no significant improvement in MD (p&gt;0.05). Parisi showed an improvement in MD after 4 months (+0.56 dB) and 6 months (+0.18 dB) of citicoline administration. Citicoline eye drops have the potential to inhibit glaucoma progression by inhibiting RNFL loss, but further research is needed on visual field improvement.</p> Metta Dewi, Ariel Valentino Soetedjo Copyright (c) 2024 Metta Dewi, Ariel Valentino Soetedjo https://creativecommons.org/licenses/by-nc/4.0 https://cdkjournal.com/index.php/cdk/article/view/1046 Thu, 01 Feb 2024 00:00:00 +0700 Peran SGLT2i terhadap Risiko Kardiorenal Pasien dengan atau Tanpa Diabetes Melitus Tipe 2 https://cdkjournal.com/index.php/cdk/article/view/873 <p>Sodium-glucose Co-transporter 2 inhibitor (SGLT2i) is one of the antidiabetic classes recommended for patients with heart and kidney problems. Evidence-based studies show the benefits of SGLT2i extend to heart, kidney, or other metabolic diseases in patients without diabetes mellitus.</p> Allen Copyright (c) 2024 Allen https://creativecommons.org/licenses/by-nc/4.0 https://cdkjournal.com/index.php/cdk/article/view/873 Thu, 01 Feb 2024 00:00:00 +0700