Transmisi Vertikal COVID 19 selama Kehamilan
DOI:
https://doi.org/10.55175/cdk.v47i9.561Keywords:
Coronavirus, kehamilan, transmisiAbstract
Penyakit Coronavirus (COVID-19) yang terjadi sejak Desember 2019 saat ini sudah menjadi pandemi global. Virus ini menimbulkan infeksi saluran pernapasan dari ringan hingga berat. Kondisi ini perlu menjadi perhatian lebih jika terjadi saat kehamilan karena perubahan fisiologi dalam kehamilan memengaruhi perjalanan virus COVID-19. Selain itu, risiko transmisi ke janin secara vertikal dan transversal juga perlu diperhatikan karena akan menimbulkan morbiditas seperti persalinan prematur, trombosis, dan pertumbuhan janin terhambat.
The Coronavirus disease (COVID-19) outbreak that occurred in December 2019 now becomes a global pandemic. The virus causes mild to severe respiratory tract infection. Infections during pregnancy may cause physiological changes that affect the course of the COVID-19 virus itself. The risk of vertical and transversal transmission to the fetus also needs to be considered as it may result in several conditions such as preterm labor, thrombosis, and fetal growth restriction.
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References
WHO. QA for public [Internet]. 2020 [cited 2020 August 20]. Available from: https://www.who.int/indonesia/news/novel-coronavirus/qa-for-public.
Info infeksi emerging Kementerian Kesehatan RI [Internet]. 2020 [cited 2020 August 20]. Available from: https://infeksiemerging.kemkes.go.id/#.
Satuan Tugas Penanganan Covid-19. Analisis data COVID-19 Indonesia. 2020 August.
Kementerian Kesehatan RI. Pedoman pelayanan bagi ibu hamil, bersalin, nifas, dan bayi baru lahir. Pedoman Pelayanan Bagi Ibu Hamil, Bersalin, Nifas dan Bayi Baru Lahir. 2019
WHO. Coronavirus disease 2019 [Internet]. 2020 [cited 2020 August 20]. Available from: https://www.who.int/docs/default-source/coronaviruse/situationreports/20200423-sitrep-94-covid-19.pdf?sfvrsn=b8304bf0_4.
Departemen Kesehatan RI. Pedoman pencegahan dan pengendalian coronavirus disease (COVID-19). Jakarta: Direktorat Jendral Pencegahan dan Pengendalian Penyakit; 2020.
Qiancheng, X, Jian S, Lingling P, Lei H, Xiaogan J, Weihua L. et al. Coronavirus disease 2019 in pregnancy. Internat J Infect Dis. 2020;95:376-83. https://doi.org/10.1016/j.ijid.2020.04.065
Sutton D, Fuchs K, D’Alton M, Goffman D. Universal screening for SARS-CoV-2 in women admitted for delivery. N Engl J Med. 2020;382(22):2163-4. https://doi.org/10.1056/nejmc2009316
Breslin N, Baptiste C, Gyamfi-Bannerman C, Miller R, Martinez R, Bernstein K, et al. Coronavirus disease 2019 infection among asymptomatic and symptomatic pregnant women: two weeks of confirmed presentations to an affiliated pair of New York City hospitals. Am J Obstetr Gynecol MFM. 2020;2(2):100118. https://doi.org/10.1016/j.ajogmf.2020.100118
Narang, Enninga E, Gunaratne M, Ibirogba E, Trad A, Elrefaei A, et al.. SARS-CoV-2 infection and COVID-19 during pregnancy: A multidisciplinary review. Mayo Clin Proc. 2020; 95(8):1750-65. https://doi.org/10.1016/j.mayocp.2020.05.011
Klok FA, Kruip MJHA, van der Meer NJM, Arbous MS, Gommers DAMPJ, Kant KM, et al. Incidence of thrombotic complications in critically ill ICU patients with COVID-19. 2020 April 10. Thromb Res. 2020;191:145–7. https://doi.org/10.1016/j.thromres.2020.04.013.
Xie Y, Wang X, Yang P, Zhang S. COVID-19 complicated by acute pulmonary embolism.Radiol Cardiothorac Imag. 2020;2(2):e200067.
Mao L, Jin H, Wang M, Hu Y, He Q, Chen S, et al. Neurologic manifestations of hospitalized patients with coronavirus disease 2019 in Wuhan, China [Internet]. JAMA Neurol. 2020;77(6):683-90. https://doi.org/10.1001/jamaneurol.2020.1127.
Dashraath P, Wong J, Lim M, Lim L, Li S, Biswas A, et al. Coronavirus disease 2019 (COVID-19) pandemic and pregnancy. Am J Obstetr Gynecol. 2020;222(6):521-31. https://doi.org/10.1016/j.ajog.2020.03.021
Cetin Gulcin U. SARS-CoV-2 during pregnancy and associated cytokine-storm. Imedpub J. 2020;6(3:1):1-3. https://doi.org/10.36648/2471-9803.6.3.1
Mor G, Aldo P, Alvero A. The unique immunological and microbial aspects of pregnancy. Nature Rev Immunol. 2017;17(8):469-82. https://doi.org/10.1038/nri.2017.64
Rcog.org.uk. Coronavirus (COVID-19) infection in pregnancy [Internet]. 2020 [cited 2020 August 23]. Available from: https://www.rcog.org.uk/globalassets/documents/guidelines/2020-07-24-coronavirus-covid-19-infection-in-pregnancy.pdf.
Dong L,Tian J, He S, Zhu C, Wang J, Liu C, et al. Possible vertical transmission of SARS-CoV-2 from an infected mother to her newborn. JAMA 2020;323(18):1846–8.doi: 10.1001/jama.2020.4621
Hosier H, Farhadian S, Morotti R, Deshmukh U, Lu-Culligan A, Campbell KH, et al. First case of placental infection with SARS-CoV-2 [Internet]. [cited 2020 May 28].Available from: https://www.medrxiv. org/content/10.1101/2020.04.30.20083907v1.full.pdf
Deniz M, Tezer H. Vertical transmission of SARS CoV-2: A systematic review. J Maternal-Fetal Neonatal Med [Internet]. 2020:1-8. Available from: https://www.tandfonline.com/doi/full/10.1080/14767058.2020.1793322
Penfield CA, Brubaker SG, Limaye MA, Lighter J, Ratner AJ, Thomas KM, et al. Detection of SARS-COV-2 in placental and fetal membrane sam- ples. Am J Obstet Gynecol MFM. 2020;2(3):100133
Zamaniyan M, Ebadi A, Aghajanpoor S, Rahmani Z, Haghshenas M, Azizi S. Preterm delivery, maternal death, and vertical transmission in a pregnant woman with COVID-19 infection. Prenat Diagn. 2020;10.1002/pd.5713.. DOI:10.1002/pd.5713
Kirtsman M, Diambomba Y, Poutanen SM, Malinowski AK, Vlachodimitropoulou E, Parks WT, et al. Probable congenital SARS-CoV-2 infection in a neonate born to a woman with active SARS-CoV-2 infection. CMAJ. 2020;192(24):647–50.
Walker KF, O’Donoghue K, Grace N, J Dorling, J L Comeau, W Li, et al. Maternal transmission of SARS-COV-2 to the neonate, and possible routes for such transmission: A systematic review and critical analysis. . BJOG: Int J Obstet Gynecol 2020;127(11):1324-36.
Carosso A, Cosma S, Borella F, Marozio L. Pre-labor anorectal swab for SARS-CoV-2 in COVID-19 pregnant patients: is it time to think about it? Eur J Obstet Gynecol Reprod Biol. 2020;249:98–9.
Kasraeian M, Zare M, Vafaei H, Asadi N, Faraji A, Bazrafshan K, et al. COVID-19 pneumonia and pregnancy; A systematic review and meta- analysis. J Matern Fetal Neonatal Med. 2020;1–8. DOI: 10.1080/14767058.2020.1763952
Martins-Filho PR, Santos VS, Santos HP, Jr.To breastfeed or not to breastfeed? Lack of evidence on the presence of SARS-CoV-2 in breastmilk of pregnant women with COVID-19. Rev Panam Salud Publica 2020;44:59. doi: 10.26633/RPSP.2020.59
Ejog.org. Pre-labor anorectal swab for SARS-CoV-2 in COVID-19 pregnant patients: is it time to think about it? [Internet]. 2020 [cited 2020 August 31]. Available from https://www.ejog.org/article/S0301-2115(20)30202-5/pdf.
Zheng QL, Duan T, Jin LP. Single-cell RNA expression profiling of ACE2 and AXL in the human maternal–fetal interface. Reprod Dev Med. 2020;4(1):7–10.
Shanes ED, Mithal LB, Otero S, Azad HA, Miller ES, Goldstein JA. Placental pathology in COVID-19. Am J Clin Pathol. 2020;154(1):23–32.
Li N, Han L, Peng M, Lv Y, Ouyang Y, Liu K, et al. Maternal and neonatal out- comes of pregnant women with COVID-19 pneumonia: A case-control study. Clin Infect Dis. 2020;ciaa352. DOI:10.1093/cid/ciaa352
WHO. Clinical management of COVID-19 [Internet]. 2020 [cited 2020 August 23]. Available from: https://apps.who.int/iris/bitstream/handle/10665/332196/WHO2019-nCoV-clinical-2020.5-eng.pdf?sequence=1&isAllowed=y.
Centers for Disease Control and Prevention (CDC). Interim considerations for infection prevention and control of coronavirus disease 2019 (COVID-19) in inpatient obstetric healthcare settings [Internet]. 2020 [cited 2020 June 10]. Available from: https://www.cdc.gov/coronavirus/2019-ncov/hcp/inpatient-obstetric-healthcare-guidance.html
Knight M, Bunch K, Tuffnell D, Shakespeare J, Kotnis R, Kenyon S, et al. Saving lives, improving mothers’ care [Internet]. 2019. Available from: https://www.npeu.ox.ac.uk/assets/downloads/mbrrace-uk/reports/MBRRACE-UK%20Maternal%20Report%202019%20-%20WEB%20VERSION.pdf
Marik PE, Kory P, Varon J. Does vitamin D status impact mortality from SARS-CoV-2 infection? Med Drug Discov 2020:100041. doi: 10.1016/j.medidd.2020.100041
Lopes de Sousa Á, Carvalho H, Oliveira L, Schneider G, Camargo E, Watanabe E, et al. Effects of COVID-19 infection during pregnancy and neonatal prognosis: What is the evidence? Internat J Environmental Res Publ Health 2020;17(11):4176. https://doi.org/10.3390/ijerph17114176
Ai T, Yang Z, Hou H, Zhan C, Chen C, Lv W, et al L. Correlation of chest CT and RT-PCR testing in coronavirus disease 2019 (COVID-19) in China: A report of 1014 cases. Radiology 2020;296(2):32-40.
WHO. Coronavirus disease 2019 (COVID-19). Sit Rep—72 [Internet]. 2020 [cited 2020 August 23]. Available from: https://www.who.int/ docs/default-source/coronaviruse/situation-reports/20200401-sitrep-72-covid-19.pdf?sfvrsn=3dd8971b_2
Hai L, Hu Z. The clinical utility of neutrophil to lymphocyte ratio in pregnancy related complications: A mini-review. J Lab Precision Med. 2020;5:1-1. https://doi.org/10.21037/jlpm.2019.10.03
Update rekomendasi POGI penanganan infeksi virus corona (COVID-19) pada maternal (hamil, bersalin dan nifas) dalam masa new normal. PP POGI. 2020.
POGI. Rekomendasi penanganan infeksi virus corona (COVID-19) pada maternal (hamil, bersalin dan nifas) [Internet]. 2020 [cited 2020 August 24]. Available from: https://pogi.or.id/publish/wp-content/uploads/2020/03/Rekomendasi-Penanganan-Infeksi-COVID-19-pada-maternal.pdf.
Mei Y, Luo D, Wei S, Liao X, Pan Y, Yang X, et al. Obstetric management of COVID-19 in pregnant women. Frontiers In Microbiology 2020;11:1186. https://doi.org/10.3389/fmicb.2020.01186
McIntosh J. Corticosteroid guidance for pregnancy during COVID-19 pandemic. Am J Perinatol. 2020;37(08):809-12. https://doi.org/10.1055/s-0040-1709684
Boelig R, Manuck T, Oliver E, Di Mascio D, Saccone G, Bellussi F, et al. Labor and delivery guidance for COVID-19. Am J Obstetr Gynecol MFM. 2020;2(2):100110.https://doi.org/10.1016/j.ajogmf.2020.100110
UpToDate. Coronavirus disease 2019 (COVID-19): Pregnancy issues [Internet]. 2020 [cited 2020 August 26]. Available from: https://www.uptodate.com/contents/coronavirus-disease-2019-covid-19-pregnancy-issues.
UpToDate. Coronavirus disease 2019 (COVID-19): Anesthetic concerns, including airway management and infection control [Internet]. 2020 [cited 2020 August 26]. Available from: https://www.uptodate.com/contents/coronavirus-disease-2019-covid-19-anesthetic-concerns-including-airway-management-and-infectioncontrol.
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