Diagnosis dan Tatalaksana Mioma Uteri
DOI:
https://doi.org/10.55175/cdk.v47i3.352Keywords:
Mioma uteri, otot polos rahim, tumor jinakAbstract
Mioma uteri merupakan tumor jinak yang menyerang otot polos rahim. Nama lainnya adalah fibroid atau leiomioma. Tumorigenesis dididuga terjadi akibat abnormalitas gen and paparan hormonal. Kasus mioma dapat terjadi pada populasi dengan rentang usia sejak menarche sampai menopause. Sebagian besar kasus tidak bergejala sehingga sering ditemukan secara tidak sengaja. Tumor ini menjadi salah satu penyebab subfertilitas. Jika bersamaan dengan kehamilan akan mengganggu perkembangan janin. Diperlukan ultrasonografi (USG) untuk konfirmasi diagnosis. Penanganan klinis meliputi observasi dan pembedahan, tergantung keluhan dan keinginan hamil.
Uterine myomas are benign uterine smooth muscle neoplasms. The synonyms are fibroids or leiomyomas. Tumorigenesis is caused by gen abnormalities and induced by hormonal interaction. This tumour can be found from menarche until menopause. Most cases are discovered incidentally. These tumours are contributing factor to subfertility and have negative implication on fetal development. Ultrasonography (USG) is required for diagnosis. Clinical approach is observation and surgery, depends on symptoms dan fertility consideration.
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References
Rafael FV, Geraldine EE. Pathophysiology of uterine myomas and its clinical implications. New York: Springer; 2015
Andrea C, Jacopo DG, Piergiorgio S, Nina M, Stefano RG, Petro L, et al. Uterine fibroids: Pathogenesis and interactions with endometrium and endomyometrial junction. Obstet Gynecol Int. 2013;2013:173184.
Persatuan obstetri dan ginekologi. Standar pelayanan medik obstetri dan ginekologi. 2006 .p. 129-30
Maria SD, Edward MB. Uterine fibroids: Diagnosis and treatment. Am Fam Physician. 2017;95(2):100-7
Alistair RW. Uterine fibroids-what’s new? Pubmed Central. 2017; 6: 2109.
Radmilla S, Ljijiana M, Antonio M, Andrea T. Epidemiology of uterine myomas: A review. Internat J Fertil Steril. 2016;9(4):424-35
Andrea T, Antonio M. Uterine myoma, myomectomy and minimally invasive treatments. New York: Springer; 2015
Hana A, Freddy WW, Hermine MMT. Karakteristik penderita mioma uteri di RSUP Prof. Dr. R.D. Kandou Manado. Jurnal Medik dan Rehabilitasi. 2019;1(3):1-6.
Aymara M, Marta T, Joana DC, Gloria E, Ignacio C, Javier M. Updated approaches for management of uterine fibroids. Internat J Women’s Health. 2017;9: 607-17
Ashish RK. Comparison between miferpristone and uliprostal acetate as an altentative to surgical management of uterine fibroids (leiomyoma) in symptomatic patients of reproductive age group in Asian population. IJRCOG. 2018;(1):109-13. DOI: http://dx.doi.org/10.18203/2320-1770.ijrcog20175528
Georgios A, Georgios D. Uterine myomas: Recent advances in their treatment. J Gynaecol Women’s Health. 2016. DOI: 10.19080/JGWH.2016.01.555560
Quaker EH. The burden of uterine fibroids: A search for primary and secondary prevention. 2019;111:150-1. https://doi.org/10.1016/j.fertnstert.2018.10.031
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