Use of Near Infrared Spectroscopy for Diabetic Foot Evaluation
Analysis
DOI:
https://doi.org/10.55175/cdk.v52i2.1208Keywords:
Diabetic foot, peripheral arterial disease, near infrared spectroscopyAbstract
Introduction: Diabetic foot disease requires serious management due to the risk of amputation. Microvascular abnormalities increase the risk of amputation by impairing blood flow, slowing wound healing, and increasing the risk of infection. Methods: Systematic review of the clinical potential of near infrared spectroscopy (NIRS) for identification of peripheral arterial disease (PAD) concomitant with diabetic (DM) microangiopathy. Systematic literature search through PubMed BMC Central published in 2018-April 2024. Discussion: NIRS can provide clues such as prediction of recovery time, deoxygenation of peripheral blood, oxygen consumption (VO2), tissue oxygen saturation (StO2), total hemoglobin (HbT), and oxyhemoglobin area under the curve (O2 HbAUC). NIRS has the potential to help predict wound healing especially in diabetic patients with symptoms masked by peripheral neuropathy. Conclusion: NIRS can assess the effectiveness of treatment and prevent worsening PAD in diabetic foot.
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References
Singh N, Armstrong DG, Lipsky BA. Preventing foot ulcers in patients with diabetes. JAMA. 2005;293(2):217-28. DOI: 10.1001/jama.293.2.217.
Yazdanpanah L, Nasiri M, Adarvishi S. Literature review on the management of diabetic foot ulcer. World J Diabetes. 2015;6(1):37-53. DOI: 10.4239/wjd.v6.i1.37.
Selvin E, Erlinger TP. Prevalence of and risk factors for peripheral arterial disease in the United States: results from the National Health and Nutrition Examination Survey, 1999–2000. Circulation. 2004;110(6):738-43. DOI: 10.1161/01.cir.0000137913.26087.f0.
Faglia E, Favales F, Quarantiello A, Calia P, Clelia P, Brambilla G, et al. Angiographic evaluation of peripheral arterial occlusive disease and its role as a prognostic determinant for major amputation in diabetic subjects with foot ulcers. Diabetes Care. 1998;21(4): 625-30. DOI: 10.2337/diacare.21.4.625.
Jude EB, Oyibo SO, Chalmers N, Boulton AJ. Peripheral arterial disease in diabetic and nondiabetic patients: A comparison of severity and outcome. Diabetes Care 2001;24(8):1433-7. DOI: 10.2337/diacare.24.8.1433.
Narres M, Kvitkina T, Claessen H, Droste S, Schuster B, Morbach S, et al. Incidence of lower extremity amputations in the diabetic compared with the non-diabetic population: A systematic review. PLoS One 2017;12(8):e0182081. DOI: 10.1371/journal.pone.0182081.
Weingarten MS, Samuels JA, Neidrauer M, Mao X, Diaz D, McGuire J, et al. Diffuse near-infrared spectroscopy prediction of healing in diabetic foot ulcers: A human study and cost analysis. Wound Repair Regen. 2012;20(6):911-7. DOI: 10.1111/j.1524-475x.2012.00843.x.
Irwin MS, Thorniley MS, Dore CJ, Green CJ. Near infra-red spectroscopy: A non-invasive monitor of perfusion and oxygenation within the microcirculation of limbs and flaps. Br J Plast Surg. 1995;48(1):14-22. DOI: 10.1016/0007-1226(95)90024-1.
Repez A, Oroszy D, Arnez ZM. Continuous postoperative monitoring of cutaneous free flaps using near infrared spectroscopy. J Plast Reconstr Aesthet Surg. 2008;61(1):71-7. DOI: 10.1016/j.bjps.2007.04.003.
McCully KK, Landsberg L, Suarez M, Hofmann M, Posner JD. Identification of peripheral vascular disease in elderly subjects using optical spectroscopy. J Gerontol Ser A, Biol Sci Med Sci. 1997;52(3):159-65. DOI: 10.1093/gerona/52a.3.b159.
Kooijman HM, Hopman MT, Colier WN, van der Vliet JA, Oeseburg B. Near infrared spectroscopy for noninvasive assessment of claudication. J Surg Res. 1997;72(1):1-7. DOI: 10.1006/jsre.1997.5164.
Harrison DK, Voss C, Vollmar HS, Koutsiaris AG, Newton DJ. Response of muscle oxygen saturation to exercise, measured with near infrared spectrophotometry in patients with peripheral vascular disease. Adv Exp Med Biol. 1998;454:45-52.
Baltrunas T, Pikturnaite G, Racyte A, Baltruniene V, Mosenko V, Skrebunas A, et al. Measurement of revascularization effect using near infrared spectroscopy in below the knee arteries. Rev Cardiovasc Med. 2022;23(9):299. DOI: 10.31083/j.rcm2309299.
Weingarten MS, Samuels JA, Neidrauer M, Mao X, Diaz D, McGuire J, et al. Diffuse near-infrared spectroscopy prediction of healing in diabetic foot ulcers: A human study and cost analysis. Wound Repair Regen. 2012;20(6):911-7. DOI: 10.1111/j.1524-475X.2012.00843.x.
Eiberg JP, Secher NH, Schroeder TV. Improved postischemic recovery after peripheral bypass surgery assessed by near-infrared spectroscopy. Vasc Surg. 1998;32(4):361-6. DOI: 10.1177/153857449803200413.
Casavola C, Paunescu LA, Fantini S, Franceschini MA, Lugara PM, Gratton E. Application of near-infrared tissue oxymetry to the diagnosis of peripheral vascular disease. Clin Hemorheol Microcirc. 1999;21(3–4):389–93. PMID: 10711775.
Seifalian AM, Atwal A, White S, Mikhailidis DP, Baker D, Hamilton G. A role for near infrared spectroscopy in the assessment of intermittent claudication. Int Angiol. 2001;20(4):301-6. PMID: 11782696.
Kragelj R,Jarm T, Erjavec T, Presern-Strukelj M, Miklavcic D. Parameters of postocclusive reactive hyperemia measured by near infrared spectroscopy in patients with peripheral vascular disease and in healthy volunteers. Ann Biomed Eng. 2001;29(4):311-20. DOI: 10.1114/1.1359451.
Comerota AJ, Throm RC, Kelly P, Jaff M. Tissue (muscle) oxygen saturation (StO2): A new measure of symptomatic lower-extremity arterial disease. J Vasc Surg. 2003;38(4):724-9. DOI: 10.1016/s0741-5214(03)01032-2.
Wolf U, Wolf M, Choi JH, Levi M, Choudhury D, Hull S, et al. Localized irregularities in hemoglobin flow and oxygenation in calf muscle in patients with peripheral vascular disease detected with near-infrared spectrophotometry. J Vasc Surg. 2003;37(5):1017-26. DOI: 10.1067/mva.2003.214.
Joseph S, Munshi B, Agarini R, Kwok RCH, Green DJ, Jansen S. Near infrared spectroscopy in peripheral artery disease and the diabetic foot: A systematic review. Diabetes Metab Res Rev. 2022;38(7):e3571. DOI: 10.1002/dmrr.3571.
Hamaoka T, McCully KK, Quaresima V, Yamamoto K, Chance B. Near-infrared spectroscopy/imaging for monitoring muscle oxygenation and oxidative metabolism in healthy and diseased humans. J Biomed Opt. 2007;12(6):062105. DOI: 10.1117/1.2805437.
Uccioli L, Meloni M, Izzo V, Giurato L, Merolla S, Gandini R. Critical limb ischemia: Current challenges and future prospects. Vasc Health Risk Manag. 2018;14:63-74. DOI: 10.2147/VHRM.S125065.
Cornelis N, Chatzinikolaou P, Buys R, Fourneau I, Claes J, Cornelissen V. The use of near infrared spectroscopy to evaluate the effect of exercise on peripheral muscle oxygenation in patients with lower extremity artery disease: A systematic review. Eur J Vasc Endovasc Surg. 2021;61(5):837-47. DOI: 10.1016/j.ejvs.2021.02.008.
Pedersen BL, Baekgaard N, Quistorff B. A near infrared spectroscopy-based test of calf muscle function in patients with peripheral arterial disease. Int J Angiol. 2015;24(1):25-34. DOI: 10.1055/s-0035-1544223.
Joseph S, Munshi B, Agarini R, Kwok RCH, Green DJ, Jansen S. Near infrared spectroscopy in peripheral artery disease and the diabetic foot: A systematic review. Diabetes Metab Res Rev. 2022;38(7):e3571. DOI:10.1002/dmrr.3571.
Regensteiner JG, Hiatt WR. Exercise rehabilitation for patients with peripheral arterial disease. Exerc Sport Sci Rev. 1995;23:1-24. PMID: 7556347.
Smith JL, Nichols WW, Skelton MM, Cowley Jr AW. Hemodynamic effects of chronic hypertension and diabetes in the dog. Hypertension. 1989;13(2):122-31. DOI: 10.1161/HYPERTENSIONAHA.121.17981.
Louvaris Z, Habazettl H, Wagner H, Zakynthinos S, Wagner P, Vogiatzis I. Near-infrared spectroscopy using indocyanine green dye for minimally invasive measurement of respiratory and leg muscle blood flow in patients with COPD. J Appl Physiol (1985). 2018 Sep 1;125(3):947-59. DOI: 10.1152/japplphysiol.00959.2017. PMID: 29927736.
McCully KK, Hamaoka T. Near-infrared spectroscopy: what can it tell us about oxygen saturation in skeletal muscle? Exerc Sport Sci Rev. 2000;28(3):123-7. PMID: 10916704.
Bohn B, Herbst A, Pfeifer M, Krakow D, Zimny S, Kopp F, et al; DPV Initiative. Impact of physical activity on glycemic control and prevalence of cardiovascular risk factors in adults with type 1 diabetes: A cross-sectional multicenter study of 18,028 patients. Diabetes Care 2015 Aug;38(8):1536-43. DOI: 10.2337/dc15-0030. PMID: 26015557.
Weingarten MS, Neidrauer M, Mateo A, Mao X, McDaniel JE, Jenkins L, et al. Prediction of wound healing in human diabetic foot ulcers by diffuse near-infrared spectroscopy: A pilot study. Wound Repair Regen. 2010; 18(2):180-5. DOI: 10.1111/j.1524-475x.2010.00583.x.
Hamaoka T, McCully KK, Niwayama M, Chance B. The use of muscle near-infrared spectroscopy in exercise sciences. Exercise Physiology. Springer; 2011 .p. 763-802.
Seiyama A, Hazeki O, Tamura M. Noninvasive quantitative analysis of blood oxygenation in rat skeletal muscle. J Biochem. 1988;103(3):419-24. DOI:10.1093/oxfordjournals.jbchem.a122284.
Boushel R, Langberg H, Olesen J, Gonzales-Alonzo J, Bulow J, Kjaer M. Monitoring tissue oxygen availability with near infrared spectroscopy (NIRS) in health and disease. Scand J Med Sci Sports. 2001;11(4):213-22. DOI:10.1034/j.1600-0838.2001.110404.x.
Haas TL, Lloyd PG, Yang HT, Terjung RL. Exercise training and peripheral arterial disease. Compr Physiol. 2012 Oct;2(4):2933-3017. DOI: 10.1002/cphy.c110065. PMID: 23720270.
Hiatt WR, Regensteiner JG, Hargarten ME, Wolfel EE, Brass EP. Benefit of exercise conditioning for patients with peripheral arterial disease. Circulation 1990 Feb;81(2):602-9. DOI: 10.1161/01.cir.81.2.602. PMID: 2404633.
Brendle DC, Joseph LJ, Corretti MC, Gardner AW, Katzel LI. Effects of exercise rehabilitation on endothelial reactivity in older patients with peripheral arterial disease. Am J Cardiol. 2001;87(3):324-9. DOI: 10.1016/s0002-9149(00)01367-9.
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