Effectiveness of mRNA-based Influenza Vaccines in Enhancing Immunity and Their Potential to Protect Children from Pneumonia Risk
Analysis
DOI:
https://doi.org/10.55175/cdk.v52i6.1619Keywords:
Vaccine, mRNA vaccine, influenza virusAbstract
Influenza viruses have posed a global threat since the 19th century, presenting serious challenges and threats to public health worldwide. Influenza viruses are among the major seasonal outbreaks impacting health and the economy yearly. Numerous new strains emerge over time due to the antigenic drift of influenza viruses, which undergo mutations. Therefore, vaccines and medical technologies continuously need innovative approaches to stimulate immune responses effectively. mRNA-based influenza vaccines are potentially more effective because of the inclusion of a broader range of antigens that can enhance cellular immunity or expand protection beyond just hemagglutinin (HA) and neuraminidase (NA), they can incorporate more than four antigens (HA) in a single formulation, offering advantages in effectiveness, safety, and rapid large-scale production. mRNA-based influenza vaccines hold significant potential and are expected to benefit children due to their various advantages.
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