Retinopati Prematuritas: Diagnosis dan Tatalaksana

Authors

  • Willy Yahya Klinik Pratama Ume Manekan, So’E, Nusa Tenggara Timur, Indonesia

DOI:

https://doi.org/10.55175/cdk.v47i8.576

Keywords:

Fotokoagulasi laser, patofisiologi, retinopati prematuritas, skrining, VEGF

Abstract

Retinopati prematuritas (ROP) adalah kelainan proliferatif progresif pembuluh darah retina bayi prematur yang dapat menyebabkan kebutaan. International Classification of Retinopathy of Prematurity (ICROP) membagi ROP berdasarkan tingkat keparahan, perluasan, lokasi, adanya penyakit lain, dan adanya ROP posterior yang agresif. ROP dimulai dari penundaan vaskulerisasi retina akibat keadaan hiperoksia relatif dan dilanjutkan dengan fase vasoproliferasi. Skrining adekuat dengan oftalmoskop indirek dan tatalaksana sesuai pedoman The Early Treatment for Retinopathy of Prematurity (ETROP) menjadi modalitas penanganan ROP saat ini. Tatalaksana dengan modalitas lain masih diteliti.

Retinopathy of prematurity (ROP) is a proliferative, progressive vascularization in premature infants which can lead to blindness. International Classification of Retinopathy of Prematurity (ICROP) classified the ROP based on severity, extent, zone, the existence of other diseases, and the existence of aggressive posterior ROP. ROP starts with the delay of retinal vascularization from relative hyperoxia state and develops to vasoproliferation phase. Adequate screening by indirect ophthalmoscope and The Early Treatment for Retinopathy of Prematurity (ETROP) treatment guideline become the current modality for ROP therapy. Treatment with other modalities is still under investigation

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References

Kurawa MS, Mohammed I, Farouk ZL, Muhammed A. Screening for retinopathy of prematurity by practicing paediatricians and ophthalmologists in nigeria: A survey of attitude and experience. Nigerian J Basic & Clinical Sci. 2018;15(2):148-51.

Kaya M, Çokakli M, Berk AT, Yaman A, Yesilirmak D, Kumral A, et al. Associations of vegf/vegf-receptor and hgf/c-met promoter polymorphisms with progression/regression of retinopathy of prematurity. Curr Eye Res. 2013;38(1):137-42.

Blencowe H, Moxon S, Gilbert C. Update on blindness due to retinopathy of prematurity globally and in india. Indian Pediatr. 2016;53:89-92.

Siswanto JE, Sauer PJ. Retinopathy of prematurity in indonesia: Incidence and risk factors. J Neonatal-Perinatal Med. 2017;10:85-90.

Gilbert C, Blencowe H. Retinopathy of prematurity: It is time to take action. Community Eye Health J. 2017;30(99):45-58.

Ahuja A, Reddy YV, Adenuga O, Kewlani D, Ravindran M, Ramakrishnan R. Risk factors for retinopathy of prematurity in a district in south india: A prospective cohort study. Oman J Ophthalmol. 2018;11(1):33-7.

Gebesce A, Haşim U, Keles E, Yildrim A, Gurler B, Yazgan H, et al. Retinopathy of prematurity: Incidence, risk factors, and evaluation of screening criteria. Turkish J Med Sci. 2016;46(2):315-20.

Hakeem AHAA, Mohamed GB, Othman MF. Retinopathy of prematurity: A study of prevalence and risk factors. Middle East African J Ophthalmol. 2012;19(3):289-94.

Hellström A, Smith LEH, Dammann O. Retinopathy of prematurity. Lancet. 2013;382(9902):1445-57.

Cavallaro G, Filippi L, Bagnoli P, Marca GL, Cristofori G, Raffaeli G, et al. The pathophysiology of retinopathy of prematurity: An update of previous and recent knowledge. Acta Ophthalmol. 2014;92(1):2-20.

Hartnett ME, Penn JS. Mechanisms and management of retinopathy of prematurity. NEJM. 2012;367:2515-26.

American AoO. Retinopathy of prematurity. In: Cantor LB, Rapuano CJ, Cioffi GA, eds. Retina and vitreous. 2015-2016 ed. Am Acad Ophthalmol. 2015: 180-91.

Chan-Ling T, Gock B, Stone J. The effect of oxygen on vasoformative cell division. Evidence that 'physiological hypoxia' is the stimulus for normal retinal vasculogenesis. Investig Ophthalmol Visual Sci. 1995;36(7):1201-14.

Smith L. Pathogenesis of retinopathy of prematurity. Acta Paediatr Suppl. 2002;91(s437):26-8.

Reynolds JD. Insights in rop. American Orthoptic J. 2014;64(1):43-53.

Rivera JC, Sapieha P, Joyal JS, Duhamel F, Shao Z, Sitaras N, et al. Understanding retinopathy of prematurity: Update on pathogenesis. Neonatol. 2011;100:343-53.

Subramanian KS, Bahri M, Vicente GV. Retinopathy of prematurity. Medscape [Internet] 2015. Available from: https://emedicine.medscape.com/article/976220-overview#a4.

Molinari A, Weaver D, Jalali S. Classifying retinopathy of prematurity. Comm Eye Health J. 2017;30(99):55-6.

Agarwal K, Jalali S. Classification of retinopathy of prematurity: From then till now. Comm Eye Health J. 2018;31(101):4-7.

Heidar K. Retinopathy of prematurity. Am Acad Ophthalmol [Internet]. 2015. Available from: https://eyewiki.aao.org/Retinopathy_of_Prematurity#cite_noteicomm_rop8-8.

Sanghi G, Dogra MR, Katoch D, Gupta A. Aggressive posterior retinopathy of prematurity in infants ≥1500 g birth weight. Indian J Ophthalmol. 2014;62(2):254-7.

Jefferies AL. Retinopathy of prematurity: An update on screening and management. Paediatrics Child Health. 2016;21(2):101-4.

Suelves AM, Shulman JP. Current screening and treatments in retinopathy of prematurity in the us. Dove Press. 2016;2016(8):37-43.

Fierson WM, Saunders RA, Good W, Palmer EA, Phelps D, Reynolds J, et al. Screening examination of premature infants for retinopathy of prematurity. Pediatrics.2013;131(1):189-95.

Lofqvist C, Andersson E, Sigurdsson J, Engstrom E, Hard A-L, Niklasson A, et al. Longitudinal postnatal weight and insuline-like growth factor i measurements in the prediction of retinopathy of prematurity. Arch Ophtalmol. 2006;124:1712-8.

Sanghi G, Narang A, Narula S, Dogra MR. Winrop algorithm for prediction of sight threatening retinopathy of prematurity: Initial experience in indian preterm infants. Indian J Ophthalmol. 2018;66(1):110-3.

Eckert GU, Filho JBF, Maia M, Procianoy RS. A predictive score for retinopathy of prematurity in very low birth weight preterm infants. Eye 2012;26(3):400-6.

Weaver DT, MD TJM. Telemedicine detection of type i rop in a distant neonatal intensive care unit. J Am Assoc Pediatr Ophthalmol Strabismus. 2012;16(3):229-33.

Wang S, Callaway N, Wallenstein M, Henderson M, Leng T, Moshfeghi D. Sundrop: Six years of screening for retinopathy of prematurity with telemedicine. Canad J Ophthalmol. 2015;50(2):101-6.

Rivera JC, Holm M, Austeng D, Morken TS, Zhou TE, Beaudry-Richard A, et al. Retinopathy of prematurity: Inflammation, choroidal degeneration, and novel promising therapeutic strategies J Neuroinflamm. 2017;14:1-14.

Aydin ÜT, Çekic O. The review of clinical use of current anti-vegf injections in retinopathy of prematurity. Retina-Vitreus/J Retina-Vitreous. 2015;23(3):189-94.

McCrory C, McCutcheon K. Retinopathy of prematurity: Causes, prevention and treatment. Br J Midwifery. 2016;24(9):632-4.

Vijayalakshmi P, Gilbert C. Following up children born preterm. Comm Eye Health J. 2017;30(99):62-4

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Published

01-10-2020

How to Cite

Yahya, W. (2020). Retinopati Prematuritas: Diagnosis dan Tatalaksana. Cermin Dunia Kedokteran, 47(8), 576–580. https://doi.org/10.55175/cdk.v47i8.576