Proton Pump Inhibitor (PPI) sebagai Farmakoterapi GERD pada Lansia
DOI:
https://doi.org/10.55175/cdk.v50i7.635Keywords:
Gastroesophageal reflux disease, lansia, proton pump inhibitorAbstract
Gastroesophageal reflux disease (GERD) merupakan salah satu penyakit gastrointestinal (GI) paling umum pada lanjut usia (lansia). Gejala GERD pada lansia umumnya atipikal dan tidak terlalu parah, namun lebih berisiko terjadi kelainan mukosa dan komplikasi. Proton pump inhibitor (PPI) masih menjadi sarana farmakoterapi terapi lini pertama pasien GERD lansia. Namun, penggunaan PPI pada lansia dikaitkan dengan beberapa efek samping. Hingga saat ini, belum ada konsensus mengenai durasi optimal penggunaan PPI pada lansia.
Gastroesophageal reflux disease (GERD) is one of the most common gastrointestinal (GI) diseases in the elderly. GERD symptoms in the elderly are generally atypical and less severe, but with a higher risk of mucosal abnormalities and complications. Proton pump inhibitor (PPI) therapy is still the first line pharmacotherapy for elderly GERD patients. However, PPI use in elderly are associated with several side effects. To date, there is no consensus yet on the optimal duration of PPI use in the elderly.
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