Heat-not-burn tobacco (HnBT): The Issue of Cigarette Product Substitutes and Their Health Impacts
Analysis
DOI:
https://doi.org/10.55175/cdk.v52i1.1224Keywords:
Heat not burn tobacco, smoking, nicotine, tobacco product substitute, tobacoAbstract
The health risks caused by cigarette smoking have led companies to develop and advertise alternative nicotine products, such as e-cigarettes and “heat-not-burn” (HnB) without burning tobacco. United States Federal Drug Administration (US FDA) approved the product I Quit Ordinary Smoking (IQOS) for commercial purposes in the United States. HnB tobacco products heats tobacco (up to 350°C) to produce nicotine aerosol that is inhaled without burning it at a much higher temperature (800°C). Reports show that 37% HnB users experienced at least one symptom, the most was sore throat (25.1%) followed by eye discomfort (22.3%). The notion that HnB tobacco product is an alternative to reduce the impact of conventional cigarettes is not entirely true. HnB tobacco can still have negative health impacts.
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References
Government HMs. Open consultation: Tax treatment of heated tobacco products [Internet]. 2017. Available from: https://www.gov.uk/government/consultations/tax-treatment-of-heated-tobacco-products.
Ludicke F, Ansari SM, Lama N, Blanc N, Bosilkovska M, Doneli A, et al. Effects of switching to a heat-not-burn tobacco product on biologically relevant biomarkers to assess a candidate modified risk tobacco product: A randomized trial. Cancer Epidemiol Biomarkers Prev. 2019 Nov;28(11):1934-43. DOI: 10.1158/1055-9965.EPI-18-0915.
Proctor C. Assessment of tobacco heating product THP1.0. Part 1: Series introduction. Regul Toxicol Pharmacol. 2018;93:1–3. DOI: 10.1016/j.yrtph.2017.09.010.
Aokage T, Tsukahara F, Fukuda Y, Nakao A. Heat-not-burn cigarettes induce fulminant acute eosinophilic pneumonia requiring extracorporeal membrane oxygenation. Respir Med Case Rep. 2019;26:87–90. DOI: 10.1016/j.rmcr.2018.12.002.
Ratajczak A, Jankowski P, Strus P, Feleszko W. Heat not burn tobacco product—A new global trend: Impact of heat-not-burn tobacco products on public health, a systematic review. Int J Env Res Public Heal. 2020;17(2):409. DOI: 10.3390/ijerph17020409.
Kamada T, Yamashita Y, Tomioka H. Acute eosinophilic pneumonia following heat-not-burn cigarette smoking. Respirol Case Rep. 2016;4(6):19–20. DOI: 10.1002/rcr2.190.
Berthet A, Jacot Sadowski I, Zurcher K, Guenin V, Gendre A, Vernez D, et al. « Heated » tobacco products: What do you need to know ? Rev Med Suisse. 2018;14(625):1935–41. PMID: 30379475.
Breathe. E-cigarettes, heat-not-burn and smokeless tobacco products. Breathe (Sheff ). 2020;16(1):161. DOI: 10.1183/20734735.ELF161. PMID: 32494306.
Caputi TL, Leas E, Dredze M, Cohen JE, Ayers JW. They’re heating up: Internet search query trends reveal significant public interest in heat-not-burn tobacco products. PLoS One. 2017;12(10):185–7. DOI: 10.1371/journal.pone.0185735. PMID: 29020019.
Qing H, Saijing Z, Wei Z, Huiming Z, Yichun Z, Wenjie L, et al. Release mechanism of nicotine in heat-not-burn tobacco products. Coresta Congr [Internet]. 2018. Available from: https://www.coresta.org/abstracts/release-mechanism-nicotine-heat-not-burn-tobacco-products-31872.html.
Simonavicius E, McNeil A, Shahab L, Brose LS. Heat-not-burn tobacco products: A systematic literature review. BMJ. 2019;28:582–94. DOI: 10.1136/tobaccocontrol-2018-054419.
Hair EC, Bennett M, Sheen E, Cantrell J, Briggs J, Fenn Z, et al. Examining perceptions about IQOS heated tobacco product: Consumer studies in Japan and Switzerland. Tob Control. 2018;27:70–3. DOI: 10.1136/tobaccocontrol-2018-054322.
Marynak KL, Wang TW, King BA, Agaku IT, Reimels EA, Graffunder CM. Awareness and ever use of “heat-not-burn” tobacco products among U.S. Adults, 2017. Am J Prev Med. 2018;55:551–4. DOI: 10.1016/j.amepre.2018.04.031.
Farsalinos KE, Yannovits N, Sarri T, Voudris V, Poulas K. Nicotine delivery to the aerosol of a heat-not-burn tobacco product: Comparison with a tobacco cigarette and e-cigarettes. Nicotine Tob Res. 2018;20(8):1004–9. DOI: 10.1093/ntr/ntx138.
Bekki K, Inaba Y, Uchiyama S, Kunugita N. Comparison of chemicals in mainstream smoke in heat-not-burn tobacco and combustion cigarettes. J UOEH. 2017;39(3):201–7. DOI: 10.7888/juoeh.39.201.
Scharf P, Rocha GHO, Sandri S, Heluany CS, Filho WRP, Farsky SHP. Immunotoxic mechanisms of cigarette smoke and heat-not-burn tobacco vapor on Jurkat T cell functions. Enviormental Pollut. 2021;268:1–15. DOI: 10.1016/j.envpol.2020.115863. PMID: 33126161
Sohal SS, Eapen MS, Naidu VGM, Sharma P. IQOS exposure impairs human airway cell homeostasis: direct comparison with traditional cigarette and e-cigarette. ERJ Open Res. 2019 Feb 11;5(1):00159-2018. DOI: 10.1183/23120541.00159-2018.
Leigh NJ, Tran PL, O’Connor RJ, Goniewicz ML. Cytotoxic effects of heated tobacco products (HTP) on human bronchial epithelial cells. Tob Control. 2018;27(Suppl 1):s26–9. DOI: 10.1136/tobaccocontrol-2018-054317. PMID: 30185530.
Czoli CD, White CM, Reid JL, Oconnor RJ, Hammond D. Awareness and interest in IQOS heated tobacco products among youth in Canada, England and the USA. Tob Control. 2019;29:89–95. DOI: 10.1136/tobaccocontrol-2018-054654. PMID: 30696783.
Kioi Y, Tabuchi T. Electronic, heat-not-burn, and combustible cigarette use among chronic disease patients in Japan: A cross-sectional study. Tob Induc Dis. 2018;16:41. DOI: 10.18332/tid/94455. PMID: 31516440.
Hagiwara SI. Effects of heat-not-burn tobacco on health are different from conventional cigarrette. Eur Respir J. 2018;52(suppl 62):PA1727. DOI: https://doi.org/10.1183/13993003.congress-2018.PA1727.
Rebuli ME, Rose JJ, Noel A, Croft DP, Benowitz NL, Cohen AH, et al. The e-cigarette or vaping product use–Associated lung injury epidemic: Pathogenesis, management, and future directions: An official American Thoracic Society workshop report. Ann Am Thorac Soc. 2023;20(1):1–17. DOI: 10.1513/AnnalsATS.202209-796ST. PMID: 36584985.
Lowe D, Coles AS, George TP, Kozak K. E-cigarettes. The Assessment and Treatment of Addiction. Elsevier; 2019. p. 43–56. DOI: 10.1016/C2016-0-05129-X.
Lumb AB. Nunn’s applied respiratory physiology. 8th Ed. Philadelphia: Elsevier; 2017.
LaMorte D, Desmond D, Ellis J, Lipkowitz S. Acute eosinophilic pneumonia: A fatal reaction to ado-trastuzumab. BMJ Case Reports. 2021;14(9):e243881. DOI: 10.1136/bcr-2021-243881. PMID: 34479891.
Kang BH, Lee DH, Roh MS, Um SJ, Kim I. Acute eosinophilic pneumonia after combined use of conventional and heat-not-burn cigarettes: A case report. Medicina. 2022;58:1527. DOI: 10.3390/medicina58111527. PMID: 36363483.
Lee CM. The impact of heated tobacco products on smoking cessation, tobacco use, and tobacco sales in South Korea. Korean J Fam Med. 2020;41(5):273. DOI: 10.4082/kjfm.20.0140. PMID: 32961046.
Grana R, Benowitz N, Glantz SA. E-cigarettes: A scientific review. Circulation. 2014;129(19):1972–86. DOI: 10.1161/CIRCULATIONAHA.114.007667. PMID: 24821826.
Peraturan Pemerintah (PP) nomor 109 tahun 2012 tentang pengamanan bahan yang mengandung zat adiktif berupa produk tembakau kesehatan [Internet]. 2012. Available from: https://peraturan.bpk.go.id/Details/5324/pp-no-109-tahun-2012.
Wakik KA. Komnas PT tegaskan IQOS harus masuk revisi PP 109/2012 karena mengandung nikotin dan zat adiktif. Republik Merdeka [Internet]. 2021. Available from: https://politik.rmol.id/read/2021/07/27/498212/komnas-pt-tegaskan-iqos-harus-masuk-revisi-pp-109-2012-karenamengandung-nikotin-dan-zat-adiktif.
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