Manifestation of Pulmonary Abnormalities in Systemic Lupus Erythematosus
Literature Review
DOI:
https://doi.org/10.55175/cdk.v52i2.1277Keywords:
Autoimmune, pulmonary disorders, systemic lupus erythematosusAbstract
Systemic lupus erythematosus (SLE) is an autoimmune disorder with a very dynamic course and various clinical manifestations. With respiratory tract involvement in 50%-70% of patients, pulmonary disorders are one of the causes of the high morbidity and mortality in SLE patients. The high mortality in SLE patients with pulmonary disorders contribute to patients' survival with a hazard ratio of 3.13. This article discusses the manifestations of pulmonary disorders in SLE patients.
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Rekomendasi.Perhimpunan.Reumatologi.Indonesia. Diagnosis dan pengelolaan lupus.eritromatosus sistemik. Perhimpunan Reumatologi Indonesia; 2019.
Rees F, Doherty M, Grainge MJ, Lanyon P, Zhang W. The worldwide incidence and prevalence of systemic lupus erythematosus: A systematic review of epidemiological studies. Rheumatology (Oxford). 2017 Nov 1;56(11):1945-961. DOI: 10.1093/rheumatology/kex260.
Mittoo S, Fell CD. Pulmonary manifestations of systemic lupus erythematosus. Semin Respir Crit Care Med. 2014 Apr;35(2):249-54. DOI: 10.1055/s-0034-1371537.
Amarnani R, Yeoh SA, Denneny EK, Wincup C. Lupus and the lungs: The assesment and management of pulmonary manifestations of systematic lupus erythematosus. Front Med (Lausanne). 2021 Jan 18:7:610257. DOI: 10.3389/fmed.2020.610257.
Velazquez ML, Highland KB. Pulmonary manifestations of systemic lupus erythematosus and Sjogren’s syndrome. Curr Opin Rheumatol. 2018 Sep;30(5):449-64. DOI: 10.1097/BOR.0000000000000531.
.Narvaez J, Borell H, Alonso FS, Figueroa IR, Longo JL, Izquierdo MG. Primary respiratory disease in patients with systemic lupus erythematosus: Data from the Spanish rheumatology society lupus registry (RELESSER) cohort. Arthritis Res Ther. 2018 Dec 19;20(1):280. DOI: 10.1186/s13075-018-1776-8.
Mathai SC, Danoff SK. Management of interstitial lung disease associated withconnective tissue disease. BMJ. 2016;352:h6819. DOI: 10.1136/bmj.h6819.
Wan SA, Teh CL, Jobli AT. Lupus pneumonitis as the initial presentation of systemic lupus erythematosus: case series from a single institution. Lupus 2016;25:1485–90. DOI: 10.1177/0961203316646461.
Murin S, Wiedemann HP, Matthay RA. Pulmonary manifestations of systemic lupus eryhtematosus. Clinics in Chest Medicine. 1998;19(4):641-65. DOI: 10.1016/s0272-5231(05)70108-8.
Shin J, Lee KH, Park S, Yang JW, Kim HJ, Song K, et al. Systemic lupus erythematosus and lung involvement : A comprehensive review. J Clin Med. 2022;11(22):6714. DOI: 10.3390/jcm11226714.
Vivero M, Padera RF. Histopatology of lung disease in the connective tissue diseases. Rheum Dis Clin North Am. 2015;41:197-211. DOI: 10.1016/j.rdc.2014.12.002.
Hannah JR, D’Cruz DP. Pulmonary complications of systemic lupus erythematosus. Semin Respir Crit Care Med.2019;40:227–34. DOI: 10.1055/s-0039-1685537.
Richter P, Cardoneanu A, Dima N, Bratoiu I, Rezus C, Burlui AM, et al. Interstitial lung disease in systemic lupus erythematosus and systemic sclerosis: How can we manage the challenge? Int J Mol Sci. 2023;24(11):9388. DOI: 10.3390/ijms24119388.
Lazovic B, Zlatkovic-Svenda M, Jasarovic D, Stevanovic D. Systemic lupus erythematosus presenting as acute lupus pneumonitis. Arch Bronconeumol. 2018;54(4):220-34. DOI: 10.1016/j.arbres.2017.08.010.
Ajakumar Menon A, Kirshenbaum D, Burke G. Drug induced lupus presenting as isolated pleural effusion. Chest. 2015;148:884A. DOI:10.1378/chest.2236839.
Costa MF, Said NR, Zimmermann B. Drug-induced lupus due to antitumor necrosis factor alpha agents. Semin Arthritis Rheum. 2008;37:381–7. DOI: 10.1016/j.semarthrit.2007.08.003.
Palavutitotai N, Buppajarntham T, Katchamart W. Etiologies and outcomes of pleural effusions in patients with systemic lupus erythematosus. J Clin Rheumatol. 2014;20:418–21. DOI: 10.1097/RHU.0000000000000179.
Gulhane S, Gangane N. Detection of lupus erythematosus cells in pleural effusion: An unusual pretentation of systemic lupus erythematosus. J Cytology. 2012;29(1):77-9. DOI: 10.4103/0970-9371.93232.
Yao X, Hamid MA, Sundaralingam A, Evans A, Karthikappallil R, Dong T. Clinical perspective and practices on pleural effusions in chronic systemic inflammatory diseases. Breathe. 2020;16(4):1-9. DOI: 10.1183/20734735.0203-2020.
Hoeper MM, Ghofrani HA, Grünig E, Klose H, Olschewski H, Rosenkranz S. Pulmonary hypertension. Dtsch Arztebl Int. 2017;114:73–84. DOI: 10.3238/arztebl.2017.0073.
Masoodi I, Sirwal IA, Anwar SK, Alzaidi A, Balbaid KA. Predictors of mortality in pulmonary haemorrhage during SLE: A single centre study over eleven years. Open Access Maced J Med Sci. 2019;7:92–6. DOI: 10.3889/oamjms.2019.038.
Bajantri B, Sapkota B, Venkatram S. Diffuse alveolar hemorrhage without extrapulmonary manifestations: A rare presentation of lupus. Am J Case Rep. 2018;19:218–23. DOI: 10.12659/AJCR.907148.
Duron L, Cohen-Aubart F, Diot E, Borie R, Abad S, Richez C, et al. Shrinking lung syndrome associated with systemic lupus erythematosus: A multicenter collaborative study of 15 new cases and a review of the 155 cases in the literature focusing on treatment response and long-term outcomes. Autoimmun Rev. 2016;15:994–1000. DOI: 10.1016/j.autrev.2016.07.021.
Toya SP, Tzelepis GE. Association of the shrinking lung syndrome in systemic lupus erythematosus with pleurisy: A systematic review. Semin Arthritis Rheum. 2009;39:30–7. DOI: 10.1016/j.semarthrit.2008.04.003.
Choudhury S, Ramos M, Anjum H, Ali M, Surani S. Shrinking lung syndrome: A rare manifestation of systemic lupus erythematosus. Cureus 2020;12(5):1-6. DOI: 10.7759/cureus.8216.
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