Effectiveness of Citicoline Adjuvant Therapy on Cognitive Improvement of Head Injury Patients
DOI:
https://doi.org/10.55175/cdk.v51i9.980Keywords:
Traumatic brain injury, citicoline, cognitive improvementAbstract
Background: Head injuries can reduce brain function with high morbidity. Several studies showed that citicoline may improve mild, moderate, and severe head injuries. Objective: To review the effectiveness of citicoline for cognitive improvement in head injury patients. Methods: Systematic search of 2 databases, ScienceDirect and Pubmed. Selected articles were then critically reviewed and analyzed. Results: Studies by Levin (1991) and Calatayud, et al, (1991) in Secades, et al. (2021); and Shokouhi, et al, (2014) showed that citicoline may improve cognitive function in adults and elderly with mild, moderate, and severe head injuries (p <0.05). Conclusion: Citicoline is effective in improving cognitive function in head injury patients.
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Copyright (c) 2024 Syafira Elfa Ramadhan, Nikmatul Hikmah Putri, Bayu Sulistio, Fery Luvita Sari
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