From CLE to SLE: A Case Report from Local Hospital

Case Report

Authors

  • Kelvin Tarumanagara University, Jakarta, Indonesia
  • Louis Rianto Tarumanagara University, Jakarta, Indonesia
  • Linda Julianti Wijayadi Dermatovenereology Department, Tarumanagara University, Jakarta, Indonesia

DOI:

https://doi.org/10.55175/cdk.v52i6.1281

Keywords:

Autoimmune disease, cutaneous lupus erythematosus, SLE

Abstract

Introduction: Lupus erythematosus (LE) is a combination of various interrelating autoimmune clinical diseases. Cutaneous lupus erythematosus (CLE) is a spectrum of typical autoimmune skin features of systemic lupus erythematosus (SLE). A good recognition of the typical appearance of this skin lesion (CLE) enables diagnosis and good management of SLE. Case: A 26-year-old female with SLE with acute skin lessions (ACLE) skin lesions. Suspicion of SLE became stronger when the antinuclear antibody (ANA) titer reached 1:3,200. The main therapy is methylprednisolone injection followed by a gradual dose reduction. The patient was treated for 6 days in hospital and all lesions improved. Conclusion: The patient in this case had SLE with 6 clinical domains in the EULAR/ACR 2019 criteria and a total score of 34 (>10). Earlier and more accurate diagnosis of SLE can make therapy more effective, especially if CLE is already present.

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Published

10-06-2025

How to Cite

Kelvin, Rianto, L., & Wijayadi, L. J. (2025). From CLE to SLE: A Case Report from Local Hospital: Case Report. Cermin Dunia Kedokteran, 52(6), 395–399. https://doi.org/10.55175/cdk.v52i6.1281