Infeksi TORCH Maternal dan Kongenital

Authors

  • Brigitta Supit Alumna Fakultas Kedokteran Universitas Gadjah Mada, Yogyakarta, Indonesia

DOI:

https://doi.org/10.55175/cdk.v48i9.133

Keywords:

kongenital, marternal, TORCH

Abstract

Infeksi perinatal secara kolektif disebut infeksi TORCH untuk toksoplasma, rubella, cytomegalovirus, HSV, dan organisme lainnya seperti HIV, parvovirus B19, enterovirus, EBV, VZV, virus hepatitis B, virus hepatitis C, campak, adenovirus, virus Zika, dan Treponema pallidum. Infeksi dapat asimptomatis atau menyebabkan gejala minor pada ibu; namun merupakan penyebab mortalitas fetal dan neonatal yang signifikan dan merupakan kontributor penting untuk morbiditas pada anak-anak. Diagnosis infeksi perinatal berpusat pada dua hal, yaitu identifikasi infeksi maternal akut (terutama infeksi primer) dan verifikasi keterlibatan fetus atau neonatus.   Perinatal infections are collectively named TORCH infections, for toxoplasma, rubella, cytomegalovirus, HSV, and other organisms such as HIV, parvovirus B19, enteroviruses, EBV, VZV, hepatitis B virus, hepatitis C virus, measles, adenovirus, and Treponema pallidum. Those infections may be silent or cause only minor symptoms in the mother; however, are significant causesof fetal and neonatalmortality and important contributors to childhood morbidity. Diagnosis of perinatal infection centerson two issues, which are identification of acute maternal infection (particularly primary infection) and verification of fetus or newborn involvement.

Downloads

Download data is not yet available.

References

McPherson RA,Pincus MR. Henry’s clinical diagnosis and management by laboratory methods. 23rd ed. St. Louis,Missouri: Elsevier; 2017.

Leung KKY, Hon KL, Yeung A, Leung AKC, Man E. Congenital infections in Hong Kong: An overview of TORCH. Hong Kong Med J. 2020;26:127-38

Neu N, Duchon J, Zachariah P. TORCH infections. Clinics in Perinatology 2015;42(1): 77–103. doi:10.1016/j.clp.2014.11.001

Jaan A, Rajnik M. Torch complex. Internet: StatPearls; 2021.

Del PizzoJ. Focus on diagnosis: Congenital infections (TORCH). American Academy of Pediatrics 2011;32;537. doi: 10.1542/pir.32-12-537.

De Jong EP, Vossen ACTM, Walther FJ, Lopriore E. How to use neonatal TORCH testing. Arch Dis Childhood-Educaton and Practice 2013;98(3):93-8. doi: 10.1136/archdischild-2012-303327

Rahbari AH, Keshavarz H, Shojaee S, Mohebali M, Rezaeian M. IgG avidity ELISA test for diagnosis of acute toxoplasmosis in humans. Kor J Parasitol. 2012;50(2):99–102. doi:10.3347/kjp.2012.50.2.99

Pinninti SG, Angara R, Feja KN, Kimberlin DW, Leach, CT, Conrad, DA, et al. Neonatal herpes disease following maternal antenatal antiviral suppressive therapy: A multicenter case series. J Pediatr. 2012;161(1):134–8. doi:10.1016/j.jpeds.2011.12.053

Yike, LD. Preventing neonatal herpes infections through maternal immunization. Future Virol. 2017;12(12):709–11. doi:10.2217/fvl-2017-0105

Downloads

Published

01-09-2021

How to Cite

Supit, B. (2021). Infeksi TORCH Maternal dan Kongenital. Cermin Dunia Kedokteran, 48(9), 376–379. https://doi.org/10.55175/cdk.v48i9.133

Issue

Section

Articles