Grape Seed Effects on Blood Pressure and Plasma Lipid Level
DOI:
https://doi.org/10.55175/cdk.v46i5.474Keywords:
Blood pressure, grape seed, hypertension, plant-derived therapeutics, plasma lipidAbstract
Grape seed is known for its antioxidative and anti-inflammatory properties. This paper discuss its benefits on human, such as reducing blood pressure and plasma lipid level, therefore reducing atherosclerosis risk and subsequently prevent cardiovascular diseases.
Biji anggur dikenal karena efek antioksidatif dan anti-inflamasi. Tulisan ini bertujuan untuk menjelaskan komponen dalam biji anggur dan manfaatnya bagi manusia, seperti efek menurunkan tekanan darah dan kadar lipid plasma, sehingga dapat mengurangi risiko aterosklerosis dan dapat mencegah penyakit kardiovaskuler.
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References
World Health Organization. Cardiovascular diseases (CVD) [Internet]. Cardiovascular. [cited 2018 Oct 28]. Available from: http://www.who.int/en/news-room/factsheets/detail/cardiovascular-diseases-(cvds)
Naziri E, Nenadis N, Mantzouridou FT, Tsimidou MZ. Valorization of the major agrifood industrial by-products and waste from Central Macedonia (Greece) for the recovery of compounds for food applications. FRIN. 2014;65:350–8.
Graf BL, Raskin I, Cefalu WT, Ribnicky DM. Plant-derived therapeutics for the treatment of metabolic syndrome. 2013;11(10):1107–15.
Piz Ä, Rde ANNAA, Vol Ä, Lade CIB. Grape seed procyanidins prevent oxidative injury by modulating the expression of antioxidant enzyme systems. 2005;6080–6.
Ma Z, Zhang H. Phytochemical constituents, health benefits, and industrial applications of grape seeds: A mini-review. Antioxidants [Internet]. 2017;6(3):71. Available from: http://www.mdpi.com/2076-3921/6/3/71
Nunes MA, Pimentel F, Costa ASG, Alves RC, Oliveira MBPP. Cardioprotective properties of grape seed proanthocyanidins: An update. Trends Food Sci Technol. 2016;57:31–9.
Garavaglia J, Markoski MM, Oliveira A, Marcadenti A. Grape seed oil compounds: Biological and chemical actions for health. Nutr Metab Insights. 2016;9:59–64.
Cao AH, Wang J, Gao HQ, Zhang P, Qiu J. Beneficial clinical effects of grape seed proanthocyanidin extract on the progression of carotid atherosclerotic plaques. J Geriatr Cardiol. 2015;12(4):417–23.
Ngamukote S, Mäkynen K, Thilawech T, Adisakwattana S. Cholesterol-lowering activity of the major polyphenols in grape seed. Molecules. 2011;16(6):5054–61.
Feringa HHH, Laskey DA, Dickson JE, Coleman CI. The effect of grape seed extract on cardiovascular risk markers: A meta-analysis of randomized controlled trials. J Am Diet Assoc [Internet]. 2011;111(8):1173–81.
Clifton PM. Effect of grape seed extract and quercetin on cardiovascular and endothelial parameters in high-risk subjects. J Biomed Biotechnol. 2004;2004(5):272–8.
Kim JK, Kim KA, Choi HM, Park SK, Stebbins CL. Grape seed extract supplementation attenuates the blood pressure response to exercise in prehypertensive men. J Med Food [Internet]. 2018;21(5):445–53. Available from: http://www.liebertpub.com/doi/10.1089/jmf.2017.0133
Park E, Edirisinghe I, Choy YY, Waterhouse A, Burton-Freeman B. Effects of grape seed extract beverage on blood pressure and metabolic indices in individuals with pre-hypertension: A randomised, double-blinded, two-arm, parallel, placebo-controlled trial. Br J Nutr. 2015;115(2):226–38.
Barona J, Aristizabal JC, Blesso CN, Volek JS, Fernandez ML. Grape polyphenols reduce blood pressure and increase flow-mediated vasodilation in men with metabolic syndrome. J Nutr [Internet]. 2012;142(9):1626–32. Available from: http://jn.nutrition.org/cgi/doi/10.3945/jn.112.162743
Ras RT, Zock PL, Zebregs YEMP, Johnston NR, Webb DJ, Draijer R. Effect of polyphenol-rich grape seed extract on ambulatory blood pressure in subjects with preand stage I hypertension. Br J Nutr. 2013;110(12):2234–41.
Sano A, Uchida R, Saito M, Shioya N, Komori Y, Tho Y, et al. Beneficial effects of grape seed extract on malondialdehyde-modified LDL. J Nutr Sci Vitaminol. 2007;174–82.
Razavi SM, Gholamin S, Eskandari A, Mohsenian N, Ghorbanihaghjo A, Delazar A, et al. Red grape seed extract improves lipid profiles and decreases oxidized lowdensity lipoprotein in patients with mild hyperlipidemia. J Med Food [Internet]. 2013;16(3):255–8. Available from: http://online.liebertpub.com/doi/abs/10.1089/jmf.2012.2408
Drago J, Williams G, Lilly L. Hypertension. In: Taylor C, editor. Patophysiology of heart disease. 6th ed. Philladelphia: Wolters Kluwer; 2016. p. 310–33
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