Herpes Zoster Lumbalis Sinistra pada Pasien Terinfeksi HIV
DOI:
https://doi.org/10.55175/cdk.v45i4.802Keywords:
Herpes zoster, infeksi HIV, virus varicella zosterAbstract
Human Immunodeficiency Virus (HIV) merupakan virus yang menyebabkan menurunnya sistem kekebalan tubuh. Diketahui adanya hubungan antara infeksi HIV dan timbulnya berbagai manifestasi penyakit pada kulit. Herpes zoster merupakan penyakit kulit yang disebabkan reaktivasi dan multiplikasi virus varicella zoster yang menetap pada ganglia sensoris setelah varicella. Kasus: seorang laki-laki usia 32 tahun dengan keluhan timbul gelembung bergerombol berisi air dengan dasar kulit eritem disertai nyeri pada betis sampai punggung kaki kiri sejak 3 hari. Pasien terinfeksi HIV sejak 7 bulan yang lalu. Didapatkan lesi vesikel herpetiformis di atas dasar eritem sesuai dermatom Lumbal 5 (L5) sinistra. Tes Tzank menunjukkan adanya sel raksasa berinti banyak. Jumlah sel CD4 212/μL.
Human Immunodeficiency Virus (HIV) may suppress the immune system. There is relationship between HIV infections with various skin manifestations. Herpes zoster is caused by reactivation and multiplication of varicella zoster virus in sensory ganglia after varicella. Case: A 32 year-old male with painful, clustered vesicle on erythematous base along left calf to foot since 3 days. He was diagnosed HIV positive 7 months ago. Physical examination showed herpetiform vesicles on erythematous base in left Lumbal 5 (L5) dermatome. Tzank test showed the presence of multinucleated giant cells. CD4 cell count is 212/μL.
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References
Schmader KE, Oxman MN. Varicella and herpes Zzoster. In: Goldsmith LA, Katz SI, Gilchrest BA, Paller AS, Leffell DJ, Wolff K, editors. Fitzpatrick`s dermatology in general medicine. 2. 8th ed. New York: McGraw Hill; 2012. p. 2383-401.
D.James W, Berger TG, Elston DM. Viral disease. Andrew`s disease of the skin clinical dermatology. 11th ed: Saunders Elsevier; 2011. p. 360-413.
Uihlein LC, Saavedra AP, Johnson RA. Cutaneous manifestasions of human immunodeficiency virus disease. In: Goldsmith LA, Katz SI, Gilchrest BA, Paller AS, Leffell DJ, Wolff K, editors. Fitzpatrick`s dermatology in general medicine. 2. 8th ed. New York: McGraw Hill; 2012. p. 2439-55.
Bruusgaard E. The mutual relation between zoster and varicella. Br J Dermatol Syph. 1932: 1-24.
Hope-Simpson RE. The nature of herpes zoster: A long-term study and a new hypothesis. Proc R Soc Med. 1965;58:9–20.
Weinberg JM. Herpes zoster: Epidemiology, natural history and common complications. J Am Acad Dermatol. 2007;57:130-5.
Dworkin RH, Johnson RW, Breuer J, Gnann JW, Levin MJ, Backonja M, et al. Recomendations for the management of herpes zoster. Clin Infect Dis. 2007;44(Suppl1):1-26.
Sterling JC. Virus infections. In: Burns T, Breathnach S, Cox N, Griffiths C, editors. Rook`s textbook of dermatology. 8th ed. Oxford: Wiley Blackwell; 2010. p. 33.1-.81.
Staikov I, Neykov N, Marinovic B, Lipozencic J, Tsankov N. Herpes zoster as a systemic disease. Clin Dermatol. 2014;32(3):424-9. doi: 10.1016/j.clindermatol.2013.11.010.
McCary J. Herpes zoster (Shingles). The health care of homeless persons. Boston: Unknown; 2010. p. 47-51.
Wolff K, Johnson RA, Saavedra AP. VZV: Herpes zoster. Fitzpatrick`s color atlas and synopsis of clinical dermatology. 7th ed. New York: McGraw Hill; 2013. p. 675-80.
Durdu M, Baba M, Seckin D. The value of Tzanck smear test in diagnosis of erosive, vesicular, bullous, and pustular skin lesions. J Am Acad Dermatol. 2008;59(6):958-64. doi: 10.1016/j.jaad.2008.07.059.
Rieger A, Chen TM, Cockerell CJ. Cutaneous manifestations of HIV infection. In: Bolognia JL, Jorizzo JL, Schaffer JV, editors. Dermatology. 2. 3rd ed. Philadelphia: Elsavier Saunders; 2012. p. 1285-302.
Chopra S, Arora U. Skin and mucocutaneous manifestations: Useful clinical predictors of HIV/AIDS. Journal of Clinical and Diagnostic Research. 2012;6(10):1695-8.
Bunker CB, Gotch F. HIV and the skin. In: Burns T, Breathnach S, Cox N, Griffiths C, editors. Rook`s textbook of dermatology. 8th ed. Oxford: Wiley Blackwell; 2010. p.35.1-.47.
Morgan MC, Bartlett BL, Cockerell CJ, Cohen PR. Cutaneous manifestations of HIV infection. In: Tyring SK, Moore AY, Lupi O, editors. Mucocutaneous manifestations viral disease. 2nd ed. Great Britain: Informa Healthcare; 2010. p. 263-339.
Rad F, Ghaderi E, Moradi G. The relationship between skin manifestations and CD4 counts among HIV positive patients. Pak J Med Sci. 2008;24:114-7.
Penneys NS. Cutaneous viral disease in AIDS In: Marks R, editor. Skin manifestations of AIDS. United States of America: Lippincott Company; 1990. p. 68-93.
Maniar J, Kamath R. HIV and HIV associated disorders. In: Tyring SK, Lupi O, Hengge UR, editors. Tropical dermatology. Philadelphia: Elsevier Churchill Livingstone;2006. p. 93-124.
Sanchez M, Friedman-Kien AE. Skin manifestations of HIV infection. In: Wormser GP, editor. AIDS and other manifestations of HIV infection. 4th ed. New York: Elsevier Science; 2003. p. 655-83.
Kutlubay Z, Engin B. Complications of herpes zoster. J Turk Acad Dermatol. 2011;5(2):1-7.
Habif TP. Warts, herpes simplex, and other viral infections. Clinical dermatology a colour guide to diagnosis and therapy. 5th ed. Missouri: Mosby Elsevier; 2010. p.454-90.
Shin BS, Na CH, song IG, Choi KC. A case of human immunodeficiency virus infection initially presented with disseminated herpes zoster. Ann Dermatol.2010;22(2):199-202.
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