Respons Radioterapi Karsinoma Serviks Stadium Lanjut Jenis Sel Skuamosa dan Adenokarsinoma di RSUD Ulin, Banjarmasin, Indonesia
Hasil Penelitian
DOI:
https://doi.org/10.55175/cdk.v52i9.1355Kata Kunci:
Adenokarsinoma, kanker serviks, karsinoma sel skuamosa, radioterapiAbstrak
Pendahuluan: Karsinoma (kanker) serviks adalah keganasan serviks/leher rahim, yang merupakan kanker paling sering pada wanita. Menurut data GLOBOCAN tahun 2022, kanker serviks menempati urutan kedelapan terbanyak. Penatalaksanaan utama kanker serviks stadium lanjut menggunakan radioterapi. Tujuan penelitian ini untuk mempelajari respons radioterapi kanker serviks stadium lanjut jenis histopatologi karsinoma sel skuamosa dibandingkan dengan adenokarsinoma di RSUD Ulin Banjarmasin. Metode: Penelitian cross-sectional dengan desain observasional analitik. Besar sampel diambil secara total sampling selama rentang waktu penelitian dari bulan Januari 2021 sampai dengan Desember 2022. Hasil: Total sampel sebanyak 128 pasien kanker serviks terdiri dari 91 karsinoma sel skuamosa dan 37 adenokarsinoma. Analisis chi-square mendapatkan asosiasi signifikan antara histopatologi dan respons terapi, kanker serviks histopatologi karsinoma sel skuamosa lebih radiosensitif dibandingkan adenokarsinoma. Simpulan: Jenis histopatologi merupakan satu-satunya karakteristik yang berhubungan signifikan dengan respons radiasi sedangkan usia, stadium, dan ukuran tumor tidak berhubungan signifikan dengan respons radiasi.
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