Hyperemesis Gravidarum-induced Encephalopathy, Gagal Ginjal, dan Kematian Janin – Laporan Kasus
Laporan Kasus
DOI:
https://doi.org/10.55175/cdk.v53i07.1903Kata Kunci:
Laporan kasus, ensefalopati, kematian janin, hiperemesis, cedera ginjalAbstrak
Pendahuluan: Hiperemesis gravidarum (HG) adalah bentuk mual dan muntah yang parah selama kehamilan yang dapat mengancam jiwa ibu dan janin jika tidak diobati dengan benar. Meskipun sebagian besar kasus sembuh dengan penanganan konservatif, beberapa kasus jarang berkembang menjadi komplikasi multisistem yang parah termasuk ensefalopati, cedera ginjal akut, dan kematian janin. Kasus: Seorang wanita berusia 22 tahun, G1P0A0, pada usia kehamilan 13 minggu, datang dengan penurunan kesadaran setelah empat minggu muntah yang tak kunjung berhenti sejak usia kehamilan 8 minggu. Pasien muntah lebih dari lima kali sehari, kesadarannya mulai menurun dalam dua hari terakhir, mengeluhkan penglihatan kabur dan tremor. Pemeriksaan fisik menunjukkan hipotensi (tekanan darah 80/45 mmHg), takikardia, dan ekstremitas dingin. Temuan laboratorium menunjukkan cedera ginjal akut (kreatinin serum 8,1 mg/dL), gangguan elektrolit berat (natrium 115,7 mmol/L, kalium 2,07 mmol/L, klorida 77,8 mmol/L), dan cedera hepatoseluler. Ultrasonografi transabdominal mengonfirmasi kematian janin pada usia kehamilan 13 minggu. Pembahasan: HG dapat memicu komplikasi yang mengancam jiwa termasuk ensefalopati Wernicke, cedera ginjal akut, dan kehilangan janin melalui mekanisme dehidrasi berat, malnutrisi, dan ketidakseimbangan elektrolit. Pengenalan dini dengan resusitasi cairan agresif, koreksi elektrolit, dan dukungan nutrisi sangat penting untuk mencegah kerusakan multisistem yang ireversibel dan meningkatkan hasil ibu dan janin. Simpulan: Komplikasi multisistem pada HG sangat berbahaya bagi ibu dan janin. Tindakan pencegahan yang tepat dan intervensi dini harus dilakukan untuk mencegah memburuknya hasil dan mengurangi risiko kematian ibu dan janin.
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Referensi
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