Nutrisi Pasien Anak dengan Chronic Kidney Disease (CKD)

Penulis

  • Martinova Sari Panggabean Departemen Medical PT. Kalbe Farma Tbk. Jakarta, Indonesia

DOI:

https://doi.org/10.55175/cdk.v49i6.240

Kata Kunci:

Anak, Nutrisi, Penyakit ginjal kronik

Abstrak

Chronic kidney disease (CKD) atau penyakit ginjal kronik adalah kerusakan ginjal yang berlangsung selama tiga bulan atau lebih, ditandai dengan kelainan struktur ataupun fungsi ginjal, baik disertai maupun tanpa penurunan laju filtrasi glomerulus (glomerular filtration rate/GFR). Anak dengan CKD berisiko mengalami gangguan nutrisi. Prevalensi malnutrisi pada anak dengan CKD dilaporkan sekitar 20%-45%. Malnutrisi pada anak dengan CKD telah terbukti meningkatkan risiko morbiditas dan mortalitas. Selain berdampak gangguan pertumbuhan, malnutrisi pada anak dengan CKD dapat meningkatkan risiko infeksi, kelemahan, depresi, penyakit kardiovaskular, hospitalisasi, dan kematian. Oleh karena itu, pemberian nutrisi yang adekuat sangat penting pada anak dengan CKD. Intervensi pemberian nutrisi dini diperlukan untuk mendukung tumbuh kejar dan merupakan komponen kunci dalam mempertahankan pertumbuhan anak dengan CKD.

Chronic kidney disease (CKD) is defined as kidney damage lasting for at least 3 months, characterized by structural and functional abnormalities of the kidneys, either with or without a decrease in the glomerular filtration rate (GFR). Children with CKD are at risk for nutritional derangements. The prevalence of malnutrition among children with CKD was 20%-45%. Malnutrition in children with CKD is associated with significant morbidity and mortality. Besides risk of growth development, malnutrition in children with CKD can increase the risk of infection, frailty, depression, cardiovascular disease, hospitalization, and death. Adequate nutrition is pivotal in children with CKD. Early nutritional intervention is important to promote catch-up growth and is key components in the preservation of growth in children with CKD.

Unduhan

Data unduhan belum tersedia.

Referensi

KDOQI clinical practice guideline for nutrition in children with CKD: 2008 update. Am J Kidney Dis. 2009;53(3 suppl 2):11-104.

Kidney Disease: Improving Global Outcomes (KDIGO) CKD work group. KDIGO 2012 clinical practice guideline for the evaluation and management of chronic kidney disease. Kidney Int Suppl. 2013;3:1–150.

Whyte DA, Fine RN. Chronic kidney disease in children. Pediatr Rev. 2008;29(10):335-41.

Ardissino G, Daccò V, Testa S, Bonaudo R, Claris-Appiani A, Taioli E, et al. Epidemiology of chronic renal failure in children: Data from the ItalKid project. Pediatrics 2003;111(4 Pt 1):382-7.

Gulati S. Chronic kidney disease in children [Internet]. 2020 Jul 21 [cited 2021 May 11]. Available from: https://emedicine.medscape.com.

Hidayati EL, Trihono PP. Admission characteristics of pediatric chronic kidney disease. Pediatrica Indonesiana 2011;51(4):192-7.

Hidayati EL. Gangguan ginjal pada anak. Kementerian Kesehatan Indonesia [Internet]. 2018 [cited 2021 May 8]. Available from: http://p2ptm.kemkes.go.id.

Becherucci F, Roperto RM, Materassi M, Romagnani P. Chronic kidney disease in children. Clin Kidney J. 2016;9(4):583-91.

Iorember FM. Malnutrition in chronic kidney disease. Front Pediatr. 2018;6:161.

Jain NG, et al. Chapter 24 - Kidney disease and nutrition in adults and children. Present Knowledge in Nutrition (Eleventh Edition). Academic Press.; 2020 .pp. 435-49.

Fouque D, Kalantar-Zadeh K, Kopple J, Cano N, Chauveau P, Cuppari L, et al. A proposed nomenclature and diagnostic criteria for protein-energy wasting in acute and chronic kidney disease. Kidney Int. 2008;73:391-8

Hanna RM, Ghobry L, Wassef O, Rhee CM, Kalantar-Zadeh K. A practical approach to nutrition, protein-energy wasting, sarcopenia, and cachexia in patients with chronic kidney disease. Blood Purif. 2020;49(1-2):202-11.

Shaw V, Polderman N, Renken-Terhaerdt J, Paglialonga F, Oosterveld M, Tuokkola J et al. Energy and protein requirements for children with CKD stages 2-5 and on dialysis-clinical practice recommendations from the Pediatric Renal Nutrition Taskforce. Pediatr Nephrol. 2020;35(3):519-31.

Román-Ortiz, Mendizábal-Oteiza S, Codoñer-Franch P. Nutrition in pediatric kidney disease. Journal of Child Science. 2018;08(01):82-9.

Cano NJ, Fouque D, Leverve XM. Application of branched-chain amino acids in human pathological states: Renal failure. J Nutr. 2006;136(1 Suppl):299-307.

Cano NJ. Branched-chain amino-acid metabolism in renal failure. Journal of Renal Nutrition. 2009;19(5S):22–4.

Hiroshige K, Sonta T, Suda T, Kanegae K, Ohtani A. Oral supplementation of branched-chain amino acid improves nutritional status in elderly patients on chronic haemodialysis. Nephrol Dial Transplant. 2001;16(9):1856-62.

Ewers B, Riserus U, Marckmann P. Effects of unsaturated fat dietary supplements on blood lipids, and on markers of malnutrition and inflammation in hemodialysis patients. J Ren Nutr. 2009;19(5):401-11.

Daud ZA Tubie B, Adams J, Quainton T, Osia R, Tubie S, et al. Effects of protein and omega-3 supplementation, provided during regular dialysis sessions, on nutritional and inflammatory indices in hemodialysis patients. Vasc Health Risk Manag. 2012;8:187-95.

Saglimbene VM, Wong G, van Zwieten A, Palmer SC, Ruospo M, Natale P, et al. Effects of omega-3 polyunsaturated fatty acid intake in patients with chronic kidney disease: Systematic review and meta-analysis of randomized controlled trials. Clin Nutr. 2020;39(2):358-68.

Escobedo-Monge MF, Ayala-Macedo G, Sakihara G, Peralta S, Almaraz-Gómez A, Barrado E, et al. Effects of zinc supplementation on nutritional status in children with chronic kidney disease: A randomized trial. Nutrients 2019;11(11):2671.

Han X, Chesney RW. The role of taurine in renal disorders. Amino Acids. 2012;43(6):2249-63.

Chesney RW, Han X, Patters AB. Taurine and the renal system. J Biomed Sci. 2010;17 Suppl 1(Suppl 1):4.

Gholipur-Shahraki T, Feizi A, Mortazavi M, Badri S. Effects of carnitine on nutritional parameters in patients with chronic kidney disease: An updated systematic review and meta-analysis. J Res Pharm Pract. 2018;7(2):57-68.

Diterbitkan

2022-06-01

Cara Mengutip

Panggabean, M. S. (2022). Nutrisi Pasien Anak dengan Chronic Kidney Disease (CKD). Cermin Dunia Kedokteran, 49(6), 320–326. https://doi.org/10.55175/cdk.v49i6.240

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