Manfaat Omega-3 Parenteral di Dunia Medis
DOI:
https://doi.org/10.55175/cdk.v46i10.415Kata Kunci:
Asam lemak omega-3, emulsi lemak, nutrisi parenteralAbstrak
Emulsi lemak intravena merupakan komponen penting nutrisi parenteral. Awalnya emulsi lemak digunakan sebagai sumber energi non-glukosa yang efisien untuk mengurangi efek samping hiperglikemia dan sebagai sumber asam lemak esensial. Penelitian menunjukkan efek omega-3 dan omega-6 pada metabolisme, inflamasi, respons kekebalan tubuh, koagulasi, dan sinyal sel, sehingga dapat bermanfaat untuk terapi bedah, kanker, dan penyakit kritis serta pada pasien yang membutuhkan nutrisi parenteral jangka panjang. Pembahasan berikut meliputi mekanisme kerja dan manfaat omega-3 di dunia medis.
Intravenous lipid emulsions are essential component of parenteral nutrition regimens, originally employed as an efficient non-glucose energy source to reduce the adverse effects of high glucose intake and provide essential fatty acids. Research demonstrates the effects of omega-3 and omega-6 polyunsaturated fatty acids (PUFA) on key metabolic functions, inflammatory, and immune response, coagulation, and cell signaling; potentially benefit surgical, cancer, and critically ill patients as well as patients requiring long-term parenteral nutrition. This review provides an overview on the mechanisms of action and benefits of omega-3 in medicine.
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