Tinjauan atas Kanker Rongga Mulut

Penulis

  • Made Bayu Permasutha Fakultas Kedokteran, Universitas Pendidikan Ganesha, Buleleng, Bali, Indonesia

DOI:

https://doi.org/10.55175/cdk.v48i3.47

Kata Kunci:

Kanker rongga mulut, lesi prakanker

Abstrak

Kanker rongga mulut merupakan keganasan daerah mulut dan rongga mulut. Beberapa faktor risiko kanker rongga mulut yang sering ditemukan di Indonesia meliputi merokok, menyirih, penggunaan tembakau, dan minuman beralkohol. Tumor rongga mulut dibagi menjadi tumor jinak, lesi prakanker, dan kanker rongga mulut. Modalitas terapi kanker rongga mulut dan orofaring berupa pembedahan, terapi radiasi, kemoterapi, targeted therapy, dan paliatif.

Oral cancer is a malignancy in the mouth and oral cavity. Some risk factors often found in Indonesia are smoking, betel chewing, tobacco use, and alcohol. Oral tumors are divided into benign tumors, precancerous lesions, and oral cancer. Therapeutic modalities for oral and oropharynx cancer consist of surgery, radiation therapy, chemotherapy, targeted therapy, and palliative.

Unduhan

Data unduhan belum tersedia.

Referensi

American Cancer Society. Cancer facts and figures 2016. Atlanta: American Cancer Society; 2016.

WHO. WHO Report on cancer. 2020

WHO-IARC (World Health Organization-International Agency for Research on Cancer). Worldwide cancer statistics. France: IARC; 2012.

Siegel RL, Miller KD, Jemal A. Cancer statistics, 2020. CA Cancer J Clin. 2020;70(1):7–30.

Maulani RI, Yusuf HY, Noormatany. Hubungan antara kadar interleukin-8 di dalam saliva dan serum darah dengan gradasi karsinoma sel skuamosa rongga mulut sebagai alternatif deteksi dini kanker rongga mulut di Indonesia. Indonesian Science Technology; 2011.

American Cancer Society. Oral cavity and oropharyngeal cancer. Atlanta: American Cancer Society; 2016

Andrews E, Seaman WT, Webster-Cyriaque J. Oropharyngeal carcinoma in non-smokers and non-drinkers: A role for HPV. Oral Oncol. 2009;45(6):486-91.

Chou YE, Hsieh MJ, Hsin CH, Chiang WL, Lai YC, Lee YH, et al. CD44 gene polymorphisms and environmental factors on oral cancer susceptibility in Taiwan. PLoS ONE 2014;9(4):e93692.

Madani A, Dikshit M, Bhaduri D. Risk for oral cancer associated to smoking, smokeless and oral dip products. Indian J Public Health 2012; 56:57-60.

Lee CH, Ko AM, Yen CF, Chu KS, Gao YJ, Warnakulasuriya S, et al. Betel-quid dependence and oral potentially malignant disorders in six Asian countries. Br J Psychiatry. 2012;201(5):383-91.

Anantharaman D, Chabrier A, Gaborieau V, Franceschi S, Herrero R, Rajkumar T, et al. Genetic variants in nicotine addiction and alcohol metabolism genes, oral cancer risk and the propensity to smoke and drink alcohol: A replication study in India. PLoS ONE 2014;9(2):e88240.

Akhter M, Ali L, Hassan Z, Khan I. Association of human papilloma virus infection and oral squamous cell carcinoma in Bangladesh. J Health Population and Nutr. 2013;31(1):65–9.

Departemen Kesehatan Republik Indonesia. Riset kesehatan dasar tahun 2013. Kementrian Kesehatan RI; 2013.

LK Widnyani Wulan Laksmi, I Gede Budhi Setiawan S. Menekan angka mortalitas kanker rongga mulut melalui skrining. J Medika Udayana 2020;9(02):1–17.

Yunita JN. Profil protein human telomerase reverse transcriptase pada sel galur karsinoma sel skuamosa rongga mulut (KSSRM) dan jaringan mukosa rongga mulut normal [Skripsi]. Jakarta: Fakultas Kedokteran Gigi Universitas Indonesia; 2008.

Pederson GW. Buku ajar praktis bedah mulut (oral surgery). Jakarta: EGC; 2013 .p. 158-9.

Medawati A. Kanker rongga mulut dan permasalahannya. Insisivia Dental J. 2013;1:87–90.

Laskaris G. Pocket atlas of oral diseases. 2nd Ed. New York: Thieme; 2006 .p. 2-5, 54-5.

Taufiqurrahman T, Herdini C. Metastasis leher tersembunyi pada karsinoma lidah T1-T2. J Kes Andalas 2014;3(3):549–62.

Ketabat F, Pundir M, Mohabatpour F, Lobanova L, Koutsopoulos S, Hadjiiski L, et al. Controlled drug delivery systems for oral cancer treatment—current status and future perspectives. Pharmaceutics 2019;11(7), 1–29.

Diterbitkan

2021-03-01

Cara Mengutip

Bayu Permasutha, M. (2021). Tinjauan atas Kanker Rongga Mulut. Cermin Dunia Kedokteran, 48(3), 133–137. https://doi.org/10.55175/cdk.v48i3.47