Perbedaan Kejadian Agitasi Pasien Pediatri PascaAnestesi Umum dengan Sevofluran atau Isofluran
DOI:
https://doi.org/10.55175/cdk.v47i1.5Kata Kunci:
Agitasi, isofluran, PAED, sevofluran, AgitationAbstrak
Pendahuluan: Agitasi adalah masalah utama yang paling sering ditemukan di bagian anestesi pediatri. Agitasi pasca-operasi sering terjadi pada anak yang menjalani anestesi dengan sevofluran. Tujuan: Menganalisis pengaruh pemberian sevofluran dan isofluran terhadap angka kejadian agitasi pasien pediatri yang menjalani anestesi umum. Metode: Penelitian double blind randomized control trial di kamar instalasi bedah sentral RSUD Dr. Moewardi Surakarta pada 36 sampel yang telah memenuhi kriteria. Sampel dibagi menjadi kelompok mendapat anestesi umum dengan sevofluran (18 sampel) dan isofluran (18 sampel). Kejadian agitasi pasca-operasi dinilai menggunakan skor Pediatric Anesthesia Emergence Delirium (PAED) pada menit ke-10, 20, dan 30. Analisis statistik menggunakan uji independent t. Hasil: Kedua kelompok memiliki karakteristik dasar homogen. Uji beda rerata skor PAED antara kedua kelompok menghasilkan nilai p = 0,505 (10 menit), p = 0,624 (20 menit), dan p = 0,240 (30 menit). Simpulan: Kejadian agitasi pasien pediatri pasca-anestesi isofluran dan sevofluran tidak berbeda signifikan (p >0,05).
Background: Agitation is a main problem in pediatric anesthesia. Post surgery agitation in pediatric patients occurred more frequently after sevoflurane anesthesia. Purpose: To analyze the incidence of emergency agitation after sevoflurane and isoflurane general anesthesia in pediatric patients. Method: A double blind randomized control trial on 36 pediatric patients in the Central Surgery Unit of RSUD Dr. Moewardi Surakarta. Samples were divided into sevoflurane general anesthesia (18 patients) and isoflurane general anesthesia (18 patients). Post surgery agitation was recorded with Pediatric Anesthesia Emergence Delirium (PAED) score in 10, 20, and 30 minutes. Statistical analysis was performed using independent t test. Result: Both groups had comparable basic characteristics. The difference in mean PAED score between the two groups had the p value of 0.505 (10 minutes), 0.624 (20 minutes), and 0.240 (30 minutes) (p >0,05). Conclusion: The incidence of post surgery emergence agitation in children after sevoflurane general anesthesia and isoflurane general anesthesia is not significantly different
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Referensi
Vlajkovic GP, Sindjelic RP. Emergence delirium in children: many questions, few answers. International Anesthesia Research Society. 2007;104(1):94-1.
Mohkamkar M, Farhoudi F, Sahebpour AA. Postanesthetic emergence agitation in pediatric patients under general anesthesia. Iran J Pediatr. 2014;24(2):184-90.
Ebert TJ, Schmid PG. Inhaled anesthesia. In: Barash PG, Cullen BF, Stoelting RK, Cahalan MK, Atock MC, editors. Handbook of clinical anesthesia. Philadelphia: Lippincott Williams & Wilkins; 2009.
Rasha G, Sinna H, Shar M. The effect ot a pre-induction bolus dose of magnesium sulphate on emergence agitation after sevoflurane anesthesia in children undergoing adenotonsillectomy. Ain Shams J Anesthesiol. 2011;4(1):75-83.
Saifee O, Solt K. Intravenous and inhalation anesthetics. In: Dunn PF, editor. Clinical anesthesia procedures of the Massachusetts General Hospital 7th ed. USA: Lippincott William & Wilkins; 2007. p. 184-9.
Saber AT, Hougaard KS. Isoflurane, sevoflurane, and desflurane. The Nordic Expert Group for Criteria Documentation of Health Risks from Chemicals. 2009;43(9):1-115.
Locatelli BG, Lim BG, Lee Ok, Ahn H, Lee DK. Emergence delirium in children: A comparison of sevoflurane and desflurane anesthesia using the pediatric anesthesia emergence delirium (PAED). Pediatric Anesthesia. 2013;23:301-8.
Weber F, Aarts A, Hagen VVD, Russchen H. Does pharmacologic treatment prevent children from emergence agitation after sevoflurane anesthesia. A systematic review. Erasmus J Med. 2012;2:2.
Cote CJ, Jerrold L, Todres D. Practice of anesthesia in infants and children. 4th ed. Elsevier Medical Books; 2009. p. 1012-3.
Kim MS, Moon BE, Lee JR. Comparison of propofol and fentanyl administered at the end of anesthesia for prevention of emergence agitation after sevoflurane anesthesia in children. Br J Anaesth, 2012;110(2):1-7.
Motoyama EK, Davis PJ. Smith’s anesthesia for infants and children. 7th ed. Mosby Elsevier Medical Books; 2006. p. 241-58.
Nasr VG, Hanallah HS. Emergence agitation in children. Middle East J Anesthesiol. 2011;21(2):175-84.
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