Perbandingan Hasil Clock Drawing Test Pasien Epilepsi dengan Terapi Karbamazepin dan Fenitoin di Rumah Sakit Jiwa Mutiara Sukma
DOI:
https://doi.org/10.55175/cdk.v45i5.781Kata Kunci:
CDT, epilepsi, fenitoin, karbamazepin, obat antiepilepsiAbstrak
Latar Belakang: Obat antiepilepsi (OAE) dapat menurunkan fungsi kognitif penderita epilepsi. Efek samping OAE terhadap fungsi kognitif dapat dievaluasi dengan menggunakan instrumen clock drawing test (CDT). Penelitian ini bertujuan untuk membandingkan hasil pemeriksaan CDT pada pasien epilepsi pengguna OAE karbamazepin dan fenitoin. Metode: Penelitian analitik komparatif observasional dengan pendekatan potong lintang. Populasi adalah 42 pasien epilepsi dengan usia >14 tahun di RSJ Mutiara Sukma. Data karakteristik pasien diuji dengan kai kuadrat, data komparasi tes CDT kedua jenis pengobatan dianalisis menggunakan uji Mann Whitney. Hasil: Dari 42 subjek penelitian, 62% menggunakan karbamazepin dan 38% menggunakan fenitoin. Tidak terdapat perbedaan bermakna jenis kelamin, usia, etiologi, tipe bangkitan, dan onset bangkitan (p>0,05), terdapat perbedaan bermakna pada pendidikan terakhir dan lama penggunaan obat (p<0,05). Tidak terdapat perbedaan bermakna skor CDT pada pasien epilepsi pengguna karbamazepin dan fenitoin (p=0,284). Simpulan: Skor CDT pasien epilepsi pengguna karbamazepin dan fenitoin di RSJ Mutiara Sukma tidak berbeda bermakna.
Background: Antiepilepsy drug (AED) can decrease cognitive function in epileptic patient. The effect of AED on cognitive function can be evaluated with clock drawing test (CDT). This study is to compare CDT score of epileptic patients on carbamazepine and phenytoin therapy. Method: A cross-sectional comparative analytic observational study on 42 epileptic patients aged >14 years old in Mutiara Sukma Mental Hospital. Patients characteristic data were analyzed with Chi-sRuare, CDT data were analyzed with Mann 8hitney. Result: Among 42 epileptic patients, 62% were using carbamazepine and 38% were using phenytoin. No significant difference in gender, age, etiology, type of seizure, onset of seizure (p>0.05), and a significant difference in highest education and duration of therapy (p<0,05). Mann-8hitney test showed no difference between CDT score of epileptic patients using carbamazepine and phenytoin (p=0,284). Conclusion: CDT score of epileptic outpatients on carbamazepine and phenytoin therapy at Mutiara Sukma Mental Hospital NTB were not significantly different.
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