Kombinasi Metoklopramid Intravena dan Klorpromazin Oral untuk Tatalaksana Persistent Hiccups di Fasilitas Layanan Primer

Penulis

  • Fatwiadi Apulita Ginting Puskesmas Pendang, Barito Selatan, Kalimantan Tengah, Indonesia

DOI:

https://doi.org/10.55175/cdk.v45i2.828

Kata Kunci:

Cegukan persisten, fasilitas layanan primer, klorpromazin oral, metoklopramid intravena, singultus

Abstrak

Cegukan (hiccup) atau singultus merupakan fenomena sehari-hari, biasanya ringan, dan dapat sembuh sendiri, namun bila berlangsung terus-menerus dapat menimbulkan tingkat morbiditas yang bermakna bahkan kematian. Penanganan ditujukan untuk mengatasi gejala dan penyebabnya. Terapi dapat berupa farmakologis ataupun non-farmakologis. Kasus persistent hiccup pada laki-laki berusia 22 tahun dapat diatasi dengan kombinasi 10 mg metoklopramid IV dan 50 mg klorpromazin oral di fasilitas layanan primer.

 

Hiccups or singultus are common phenomenon in daily life, usually benign and self-limiting, however prolonged attacks are associated with significant morbidity even death. Therapy is directed towards symptoms and the cause. Treatment may be pharmacologic or non-pharmacologic. A 22 year-old male with persistent hiccups was managed succesfully in primary care setting with 10 mg intravenous metoclopramide plus 50 mg oral chlorpromazine.

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Referensi

Steger M, Schneemann M, Fox M. Systemic review: The pathogenesis and pharmacological treatment of hiccups. Alient Pharmacol Ther. 2015;42(9):1037-50.

Wilkes G, Dronen SC. Hiccups. Medscape [Internet]. 2016. Available from: http://emedicine.medscape.com/article/775746.

Howard RS, Charmers RM. Cause and treatment of persistent hiccups. The NatMed J India 1966;9(3):104-6.

Davignon A, Larieux G, Genest J. Chlorpromazine in the treatment ofstubborn hiccup. Union Med Can. 1955;84:282.

Friedgood CE, Ripstein CB. Chlorpromazine (thorazine) in thetreatment of intractable hiccups. J Am Med Assoc. 1955;157:309–10.

Wang T, Wang D. Metoclopramide for patients with intractable hiccups: A multicentre, randomised, controlled pilot study. Intern Med J. 2014;44(12a):1205-9

Moretti R, Torre P, Antonello RM, Ukmar M, Cazzato G, Bava A. Gabapentin as a drug therapy of intractable hiccup because of vascular lesion: A three-year follow up. Neurologist. 2004;10(2):102-6.

Zhang C, Zhang R, Zhang S, Xu M, Zhang S. Baclofen for stroke patientswith persistent hiccups: A randomized, double-blind, placebo-controlled trial. Trials 2014;15:295.

Guelaud C, Similowski T, Bizec JL, Cabane J, Whitelaw WA, Derenne JP. Baclofen therapy for chronic hiccup. Eur Respir J. 1995; 8:235–7.

Neuhaus T, Ko YD, Stier S. Succesful treatment of intractable hiccups by oral applicatin of lidocaine. Support Care Cancer 2012;20(11):3009.

Lee GW, Kim RB, Go SI, Cho HS, Lee SJ, Hui D, et al. Gender differences in hiccup patients: Analysis of published case reports and case-control studies. J Pain Symptom Manage. 2016;51(2):278-83. doi: 10.1016/j.jpainsymman.2015.09.013

Diterbitkan

2018-02-01

Cara Mengutip

Ginting, F. A. (2018). Kombinasi Metoklopramid Intravena dan Klorpromazin Oral untuk Tatalaksana Persistent Hiccups di Fasilitas Layanan Primer. Cermin Dunia Kedokteran, 45(2), 115–118. https://doi.org/10.55175/cdk.v45i2.828

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