Sindrom Chorea Hiperglikemia Ganglia Basalis

Case Report

Authors

  • Amelia Puspita Department of Neurology, Wangaya Regional General Hospital, Denpasar, Bali, Indonesia
  • I Ketut Sumada Department of Neurology, Wangaya Regional General Hospital, Denpasar, Bali, Indonesia
  • Ni Ketut Candra Wiratni Department of Neurology, Wangaya Regional General Hospital, Denpasar, Bali, Indonesia
  • Desie Yuliani Department of Neurology, Wangaya Regional General Hospital, Denpasar, Bali, Indonesia
  • Ni Made Kurnia Dwi Jayanthi Department of Neurology, Wangaya Regional General Hospital, Denpasar, Bali, Indonesia

DOI:

https://doi.org/10.55175/cdk.v51i7.963

Keywords:

Chorea, diabetes mellitus, movement disorder, chorea hyperglycemic basal ganglia syndrome

Abstract

Background: Chorea hyperglycemia basal ganglia (C-H-BG) syndrome is an uncommon manifestation of diabetes mellitus seen in patients with poor glycemic control. Case: A 74-year-old poorly controlled diabetic women with acute onset of movement disorder in the form of uncontrolled choreiform movements of her left upper and lower extremity. Her initial glucose level was 289 mg/dL and HbA1C was 9.5%. Discussion: Most C-H-BG patients are older Asian female. Female predisposition is probably related to the estrogen decline during menopause, resulting in gamma-aminobutyric acid (GABA) depletion or dopamine receptors hypersensitivity and enhancement of dopaminergic system. Its pathophysiology has not been entirely defined. Conclusion: C-H-BG is a rare manifestation of poorly controlled diabetes. Early recognition and treatment of elevated blood glucose levels appear to lead to total resolution.

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References

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Published

01-07-2024

How to Cite

Puspita, A., Sumada, I. K., Wiratni, N. K. C., Yuliani, D., & Jayanthi, N. M. K. D. (2024). Sindrom Chorea Hiperglikemia Ganglia Basalis: Case Report. Cermin Dunia Kedokteran, 51(7), 393–395. https://doi.org/10.55175/cdk.v51i7.963