Diagnosis and Management of Post-Traumatic Stress Disorder

Literature Review

Authors

  • Wenly Susanto Rumah Sakit Umum Daerah Sumber Glagah, Mojokerto, Jawa Timur, Indonesia

DOI:

https://doi.org/10.55175/cdk.v52i10.1624

Keywords:

Stress disorder, post-traumatic stress disorder, PTSD

Abstract

Post-traumatic stress disorder (PTSD) is a stress disorder that can disrupt social life due to cognitive and mood changes. The etiology of PTSD involves a combination of biological, psychological, and social factors, which interact to cause post-traumatic stress disorder. Biological factors such as genetics also play a role. Exposure to traumatic stressors in PTSD needs to be distinguished from ordinary stressors. According to the DSM-V, the diagnostic criteria for PTSD for adults, adolescents, and children over 6 years of age consist of criterion A (stressor), criterion B (intrusive symptoms), criterion C (avoidance symptoms), criterion D (changes in negative cognition and mood), criterion E (changes in reactivity and vigilance), criterion F (symptom duration), and criteria G and H. Diagnosis of PTSD is a challenge in medical practice. PTSD treatment consists of psychotherapy and pharmacotherapy. Psychotherapy is considered more efective but requires a longer time commitment, so maintaining patient engagement is crucial to improving prognosis. Appropriate management can help reduce PTSD symptoms.

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References

Mann SK, Marwaha R, Torrico TJ. Posttraumatic stress disorder [Internet]. Treasure Island (FL): StatPearls Publishing; 2024 [cited 2024 September 8]. Available from: https://www.ncbi.nlm.nih.gov/books/NBK559129/.

Al Jowf GI, Ahmed ZT, Reijnders RA, de Nijs L, Eijssen LMT. To predict, prevent, and manage post-traumatic stress disorder (PTSD): a review of pathophysiology, treatment, and biomarkers. Int J Mol Sci. 2023;24(6):5238. https://doi.org/10.3390/ijms24065238.

Sareen J. Posttraumatic stress disorder in adults: epidemiology, pathophysiology, clinical features, assessment, and diagnosis. Uptodate [Internet]. 2022 [cited 2024 September 8]. Available from: https://www.uptodate.com/contents/posttraumatic-stress-disorder-in-adults-epidemiology-pathophysiology-clinical-features-assessment-and-diagnosis.

Hofman AN, Taylor AN. Stress reactivity after traumatic brain injury: implications for comorbid post-traumatic stress disorder. Behav Pharmacol. 2019 Apr;30(2-):115–21. doi: 10.1097/FBP.0000000000000461.

Biresaw MS, Gebeyehu ET. Post-traumatic stress disorder and its associated factors among people who experienced traumatic events in east African countries, 2020: a protocol for systematic review and meta-analysis. Ann Gen Psychiatry 2021 Jan 9;20:4. doi: 10.1186/s12991-020-00324-0.

Saeed SA, Gargano SP. Natural disasters and mental health. Int Rev Psychiatry 2022 Feb;34(1):16-25. doi: 10.1080/09540261.2022.2037524.

Koenen KC, Ratanatharathorn A, Ng L, McLaughlin KA, Bromet EJ, Stein DJ, et al. Posttraumatic stress disorder in the world mental health surveys. Psychol Med. 2017 Oct;47(13):2260-74. doi: 10.1017/S0033291717000708.

Downs L Rahmadian A, Noviawati E, Vakil G, Hendriani S, Masril, Kim DA. DSM comparative study of PTSD incidence in Indonesia. Adv Soc Sci Res J. 2017; 4(12):200-12. https://doi.org/10.14738/assrj.412.3414.

Hu K. An analysis of the etiology of post-traumatic stress disorder. SHS Web of Conferences 2024;193:03006. doi:10.1051/shsconf/202419303006.

Miller MW, Wolf EJ, Logue MW, Baldwin CT. The retinoid-related orphan receptor alpha (RORA) gene and fear-related psychopathology. J Afect Disord. 2013 Aug 17;151(2):702–8. doi: 10.1016/j.jad.2013.07.022.

Lowe SR, Meyers JL, Galea S, Aiello AE, Uddin M, Wildman DE, et al. RORA and posttraumatic stress trajectories: main efects and interactions with childhood physical abuse history. Brain Behav. 2015 Mar 8;5(4):e00323. doi: 10.1002/brb3.323.

Amstadter AB, Sumner JA, Acierno R, Ruggiero KJ, Koenen KC, Kilpatrick DG, et al. Support for association of RORA variant and post traumatic stress symptoms in a population-based study of hurricane exposed adults. Mol Psychiatry. 2013 Jan 15;18(11):1148–9. doi: 10.1038/mp.2012.189.

Abdallah CG, Averill LA, Akiki TJ, Raza M, Averill CL, Gomaa H, et al. The neurobiology and pharmacotherapy of posttraumatic stress disorder. Annu Rev Pharmacol Toxicol. 2019 Jan 6:59:171-89. doi: 10.1146/annurev-pharmtox-010818-021701.

Aliev G, Beeraka NM, Nikolenko VN, Svistunov AA, Rozhnova T, Kostyuk S, et al. Neurophysiology and psychopathology underlying PTSD and recent insights into the PTSD therapies-a comprehensive review. J Clin Med. 2020 Sep 12;9(9):2951. doi: 10.3390/jcm9092951.

Miao XR, Chen QB, Wei K, Tao KM, Lu ZJ. Posttraumatic stress disorder: from diagnosis to prevention. Mil Med Res. 2018 Sep 28;5:32. doi: 10.1186/s40779-018-0179-0.

American Psychiatric Association. Diagnostic and statistical manual of mental disorders 5th ed. 2013. p. 271-2.

Depkes RI. 2000. Pedoman Penggolongan dan Diagnosis Gangguan Jiwa III(PPDGJ-III). Direktorat Kesehatan Jiwa Depkes RI

Bryant RA, Nickerson A, Creamer M, O’Donnell M, Forbes D, Galatzer-Levy I, et al. Trajectory of post-traumatic stress following traumatic injury: 6-year follow-up. British J Psychiatr. 2015;206(5):417–23. doi:10.1192/bjp.bp.114.145516.

Morganstein JC, Wynn GH, West JC. Post-traumatic stress disorder: update on diagnosis and treatment. BJPsych Advances. 2021;27(3):184–6. doi:10.1192/bja.2021.13.

Bisson JI, Berliner L, Cloitre M, Forbes D, Jensen TK, Lewis C, et al. The international society for traumatic stress studies new guidelines for the prevention and treatment of posttraumatic stress disorder: methodology and development process. JTrauma Stress. 2019;32(4):475-83. JTrauma Stress. 2019 Aug;32(4):475-83. doi: 10.1002/jts.22421.

Schrader C, Ross A. A review of PTSD and current treatment strategies. Mo Med. 2021;118(6):546-51. PMID: 34924624

Moring JC, Dondanville KA, Fina BA, Hassija C, Chard K, Monson C, et al. Cognitive processing therapy for posttraumatic stress disorder via telehealth: practical considerations during the COVID-19 pandemic. J Trauma Stress. 2020 Jun 11;33(4):371–9. doi: 10.1002/jts.22544.

Mclean CP, Foa EB. State of the science: prolonged exposure therapy for the treatment of posttraumatic stress disorder. J Trauma Stress. 2024 Aug;37(4):535-50. doi: 10.1002/jts.23046.

Gainer D, Alam S, Alam H, Redding H. A FLASH OF HOPE: eye movement desensitization and reprocessing (EMDR) therapy. Innov Clin Neurosci. 2020 Jul 1;17(7-9):12–20. PMID: 33520399.

Stein MB. Posttraumatic stress disorder in adults: treatment overview. Uptodate [Internet]. 2024 [cited 2024 September 11]. Available from: https://www.uptodate.com/contents/posttraumatic-stress-disorder-in-adults-treatment-overview.

Published

08-10-2025

How to Cite

Susanto, W. (2025). Diagnosis and Management of Post-Traumatic Stress Disorder: Literature Review. Cermin Dunia Kedokteran, 52(10), 646–650. https://doi.org/10.55175/cdk.v52i10.1624