Short-Term High Fiber, Diabetes-Specific Enteral Nutrition in an Elderly Patient with Type 2 Diabetes Mellitus: A Case Report

Case Report

Authors

  • Yustina Rossa Simatupang Instalasi Gizi RSUD Serpong Utara, South Tangerang City, Banten Province/Department of Nutrition, Faculty of Medicine, Universitas Indonesia
  • Andrean Wangsa Department of Nutrition, Faculty of Medicine, Universitas Indonesia – Dr.Cipto Mangunkusumo General Hospital, Jakarta
  • Anastu Regita Nareswara Nutrition Department, Health Polytechnic of the Ministry of Health Jakarta II
  • Melinda Setiyaningrum Indonesian Research Partnerships on Infectious Diseases (INA-RESPOND), Jakarta
  • Dendy Daffa Anugrah Putra Faculty of Medicine, Syarif Hidayatullah State Islamic University, Jakarta, Indonesia

DOI:

https://doi.org/10.55175/cdk.v53i03.2069

Keywords:

Case report, diabetes-specific formula, glycemic control, oral nutritional supplement, type 2 diabetes mellitus

Abstract

Introduction: High-fiber diabetes-specific formulas (DSFs) are designed to support glycemic control in patients with type 2 diabetes mellitus (T2DM), particularly those requiring nutritional support. Despite their potential benefits, evidence regarding their short-term effects on blood glucose levels and insulin requirements remains limited. This case report explores the impact of an oral DSF on glycemic control in an elderly patient with T2DM over a four-day inpatient period. Case: A 70-year-old overweight woman (BMI 24.6 kg/m²) was hospitalized due to
uncontrolled hyperglycemia (HbA1c 10.6%, fasting glucose 469 mg/dL) with poor oral intake (< 50% of needs) secondary to nausea and vomiting. A standardized DSF was administered orally alongside a diabetic soft diet for 4 days. DSF was introduced at 150 mL three times daily and titrated to 200 mL twice daily, contributing to a total intake of approximately 1,500 kcal/day. Insulin doses (10 IU regular insulin three times a day) remained unchanged. Monitoring included daily fasting glucose and clinical tolerance. Fasting blood glucose decreased from 469 mg/dL on day 1 to 260 mg/dL by day 4. The patient showed improved oral intake (up to 75% of caloric needs) and better appetite without gastrointestinal complaints. No hypoglycemia episodes or insulin dose adjustments were necessary. Discussion: During the four-day observation period, fasting blood glucose decreased progressively from 469 mg/dL to 260 mg/dL without modification of insulin dosage. Oral intake improved to approximately 75% of estimated needs, and no hypoglycemic episodes or gastrointestinal intolerance were observed. The improvement in glycemic trends occurred alongside structured nutritional support and consistent insulin therapy. Conclusion: Short-term administration of a high-fiber DSF improved glycemic trends and nutritional intake in an elderly T2DM patient without adverse effects. DSF can be an effective adjunct in individualized medical nutrition therapy to support glycemic stabilization during hospitalization.

Downloads

Download data is not yet available.

References

Goux A, Breyton AE, Meynier A, Lambert-Porcheron S, Sothier M, Van Den Berghe L, et al. Design and validation of a diet rich in slowly digestible starch for type 2 diabetic patients for significant improvement in glycemic profile. Nutrients. 2020;12(8):2404. https://doi.org/10.3390/nu12082404.

Nitzke D, Czermainski J, Rosa C, Coghetto C, Fernandes SA, Carteri RB. Increasing dietary fiber intake for type 2 diabetes mellitus management: a systematic review. World J Diabetes. 2024;15(5):1001–10. https://doi.org/10.4239/wjd.v15.i5.100.

Badan Kebijakan Pembangunan Kesehatan. Survei kesehatan Indonesia (SKI) 2023 dalam angka. Jakarta: Kementerian Kesehatan Republik Indonesia [Internet]. 2023. Available from: https://www.badankebijakan.kemkes.go.id/ski-2023-dalam-angka/.

Izzo A, Massimino E, Riccardi G, Della Pepa G. A narrative review on sarcopenia in type 2 diabetes mellitus: prevalence and associated factors. Nutrients. 2021;13(1):183. https://doi.org/10.3390/nu13010183.

Simon MG, Batubara SO. The correlation of food and physical activity with diabetes incidence among older-adult. Indones Nurs J Educ Clin INJEC. 2020;5(2):166. https://dx.doi.org/10.24990/injec.v5i2.286.

Di Angelantonio E, Kaptoge S, Wormser D, Willeit P, Butterworth AS, Bansal N, et al. Association of cardiometabolic multimorbidity with mortality. JAMA. 2015;314(1):52. https://doi.org/10.1001/jama.2015.7008.

Strain WD, Hope SV, Green A, Kar P, Valabhji J, Sinclair AJ. Type 2 diabetes mellitus in older people: a brief statement of key principles of modern day management including the assessment of frailty. A national collaborative stakeholder initiative. Diabet Med. 2018;35(7):838–45. https://doi.org/10.1111/dme.13644.

Tamura Y, Omura T, Toyoshima K, Araki A. Nutrition management in older adults with diabetes: a review on the importance of shifting prevention strategies from metabolic syndrome to frailty. Nutrients. 2020;12(11):3367. https://doi.org/10.3390/nu12113367.

Nie Q, Gao H, Li M, Sun Y, Chen H, Zuo S, et al. Not all dietary fibers alleviate type 2 diabetes. Research Square 2020. https://doi.org/10.21203/rs.3.rs-23527/v2.

Chandalia M, Garg A, Lutjohann D, Von Bergmann K, Grundy SM, Brinkley LJ. Beneficial effects of high dietary fiber intake in patients with type 2 diabetes mellitus. N Engl J Med. 2000;342(19):1392–8. https://doi.org/10.1056/nejm200005113421903.

Giraldo Gonzalez GC, Gonzalez Robledo LM, Jaimes Montana IC, Benjumea Salgado AM, Pico Fonseca SM, Arismendi Solano MJ, et al. Nutritional interventions in older persons with type 2 diabetes and frailty: a scoping systematic review. J Cardiovasc Dev Dis. 2024;11(9):289. https://doi.org/10.3390/jcdd11090289.

Mechanick JI, Marchetti A, Hegazi R, Hamdy O. Diabetes-specific nutrition formulas in the management of patients with diabetes and cardiometabolic risk. Nutrients 2020;12(12):3616. https://doi.org/10.3390/nu12123616.

Mesejo A, Montejo-Gonzalez JC, Vaquerizo-Alonso C, Lobo-Tamer G, Zabarte-Martinez M, Herrero-Meseguer JI, et al. Diabetes-specific enteral nutrition formula in hyperglycemic, mechanically ventilated, critically ill patients: a prospective, open-label, blind-randomized, multicenter study. Crit Care. 2015;19(1):390. https://doi.org/10.1186/s13054-015-1108-1.

Sanz-Paris A, Boj-Carceller D, Lardies-Sanchez B, Perez-Fernandez L, Cruz-Jentoft A. Health-care costs, glycemic control and nutritional status in malnourished older diabetics treated with a hypercaloric diabetes-specific enteral nutritional formula. Nutrients. 2016;8(3):153. https://doi.org/10.3390/nu8030153.

Hamdy O, Ernst FR, Baumer D, Mustad V, Partridge J, Hegazi R. Differences in resource utilization between patients with diabetes receiving glycemia-targeted specialized nutrition vs standard nutrition formulas in U.S. hospitals. J Parenter Enter Nutr. 2014;38(2S). https://doi.org/10.1177/0148607114550315.

Mesa Garcia MD, Garcia-Rodriguez CE, Rico MDLC, Aguilera CM, Perez-Rodriguez M, Perez-de-la-Cruz AJ, et al. A new fructose-free, resistant-starch type IV-enriched enteral formula improves glycaemic control and cardiovascular risk biomarkers when administered for six weeks to elderly diabetic patients. Nutr Hosp. 2017;34(1):73–80. doi: 10.20960/nh.978.

Soelistijo S. Pedoman Pengelolaan dan pencegahan diabetes melitus tipe 2 dewasa di Indonesia 2021. PERKENI [Internet]. 2021 [cited 2025 Jul 29]. Available from: https://pbperkeni.or.id/wp-content/uploads/2021/11/22-10-21-Website-Pedoman-Pengelolaan-dan-Pencegahan-DMT2-Ebook.pdf.

Elia M, Ceriello A, Laube H, Sinclair AJ, Engfer M, Stratton RJ. Enteral nutritional support and use of diabetes-specific formulas for patients with diabetes: a systematic review and meta-analysis. Diabetes Care. 2005;28(9):2267–79. doi: 10.2337/diacare.28.9.2267.

Alish CJ, Garvey WT, Maki KC, Sacks GS, Hustead DS, Hegazi RA, et al. A diabetes-specific enteral formula improves glycemic variability in patients with type 2 diabetes. Diabetes Technol Ther. 2010;12(6):419–25. https://doi.org/10.1089/dia.2009.0185

Eckert I, Kumbier MCC, Silva FM, Franzosi OS, De Almeida JC. Association of specialized enteral nutrition with glycemic control and clinical outcomes in critically ill patients: a meta-analysis of randomized controlled trials. Clin Nutr. 2021;40(6):3940–9. https://doi.org/10.1016/j.clnu.2021.04.030.

Colberg SR, Sigal RJ, Yardley JE, Riddell MC, Dunstan DW, Dempsey PC, et al. Physical activity/exercise and diabetes: a position statement of the American Diabetes Association. Diabetes Care 2016;39(11):2065–79. https://doi.org/10.2337/dc16-1728.

Anindhita B, Singal AM, Wardhani WI, Manikam NRM, Aditianingsih D. Olive oil and vegetable extract in modified hospital enteral formula improves glycemic variability in critically-ill diabetic ketoacidosis obese patient: a case report. Maj Anest Crit Care. 2024;42(1):56–67. https://doi.org/10.55497/majanestcricar.v42i1.315.

Pantanetti P, Cangelosi G, Sguanci M, Morales Palomares S, Nguyen CTT, Morresi G, et al. Glycemic control in diabetic patients receiving a diabetes-specific nutritional enteral formula: a case series in home care settings. Nutrients 2024;16(16):2602. https://doi.org/10.3390/nu16162602.

Downloads

Published

10-03-2026

How to Cite

Simatupang, Y. R., Wangsa, A., Nareswara, A. R., Setiyaningrum, M., & Putra, D. D. A. (2026). Short-Term High Fiber, Diabetes-Specific Enteral Nutrition in an Elderly Patient with Type 2 Diabetes Mellitus: A Case Report: Case Report. Cermin Dunia Kedokteran, 53(03), 172–179. https://doi.org/10.55175/cdk.v53i03.2069