Terapi Berbasis Sel: Perkembangan Terkini
DOI:
https://doi.org/10.55175/cdk.v49i3.207Keywords:
Imunoterapi, sistem imunAbstract
Terapi berbasis sel mulai mendapat perhatian ketika James P. Allison dan Tasuku Honjo mendapat hadiah Nobel bidang fisiologi/kedokteran pada tahun 2018 atas penemuan mekanisme inhibisi regulasi sel T dalam sistem imun, yang sangat berguna untuk memajukan modalitas imunoterapi. Terapi berbasis sel sejauh ini menggunakan dua jenis sel, yaitu sel imun dan sel punca. Terapi berbasis sel potensial sebagai terapi medis di masa depan, meskipun kini masih dalam tahap penelitian. Artikel ini bertujuan memberikan pengantar seputar terapi berbasis sel dan perkembangan terkininya.
Cell-based therapies start to gain attention when Nobel prize in physiology/medicine was awarded to James P. Allison and Tasuku Honjo in 2018 for their discovery in immune system’s T cell inhibition mechanism which is very valuable in immunotherapy. To date, cell-based therapies consist of two types of cells: immune cells and stem cells. Cell-based therapies are deemed future therapy in medicine, although their use are currently still in the research phase. This review is an overview and recent updates regarding cell-based therapies.
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