Leiner’s Disease (Erythroderma Desquamativum) in a Baby Boy
DOI:
https://doi.org/10.55175/cdk.v50i7.957Keywords:
Erythroderma desquamativum, dermatitis seboroik infantil, penyakit LeineAbstract
Background: Leiner’s disease (erythroderma desquamativum) is a disorder in infants; it is a complication of seborrheic dermatitis with universal and scaly erythema (erythroderma). The case is a baby boy aged 1 month 18 days with white scaly skin for 10 days and fever for 3 days prior to hospital admission. The prognosis is good with the risk of severe infections such as pneumonia, meningitis, and sepsis if not properly treated.
Latar Belakang: Penyakit Leiner (erythroderma desquamativum) adalah gangguan pada bayi yang merupakan komplikasi dermatitis seboroik; biasanya ditemukan eritema universal dan skuama (eritroderma). Kasus pada seorang bayi laki-laki berumur 1 bulan 18 hari dengan kulit kemerahan serta bersisik putih kekuningan sejak 10 hari sebelum masuk RS dan demam selama 3 hari. Prognosis baik dengan risiko infeksi berat seperti pneumonia, meningitis, dan sepsis jika tidak diterapi dengan baik.
Downloads
References
Plewig G, Jansen T. Seborrheic dermatitis. In: Wolff K, Goldsmith L, Katz S, Gilchrest B, Paller A, Lefell D, eds. Fitzpatrick’s dermatology in general medicine. Vol 1. 7th ed. New York, NY: McGraw-Hill; 2008 .p. 219-21.
Braun M, Elgart M.L. Leiner disease. NORD: Guide to rare disorders. Philadelphia, USA: Lippincott A WoltersKluwer Co.; 2003 .p. 123-4.
Hamm H. Neonatal erythroderma and immunodeficiency (previously called leiner’s disease). In: Harper J, Oranje A, Praso N, eds. Textbook of pediatric dermatology. Vol 2. 2nd Ed. Victoria, Australia: Blackwell Publ.; 2006 .p. 309.
Mc.Millan J, Feigin RD, DeAngelis C, Jones MD. Leiner disease. Oski’s pediatric: Principle and practice. 4th ed. Philadepia, USA: Lippincott Williams and Wilkin; 2004 .p. 856
Schmidt T. Seborrheic dermatitis. In: Abeck D, Burgdorf W, Cremer H, eds. A common skin disease in children. Munchen, Germany: Steinkopff Verlag Darmstadt; 2003 .p. 111-4
Bissonette B, Luginbuehl I, Marciniak B, Dalens B. Leiner syndrome. Syndromes rapid recognitions and perioperative implication. USA: The McGraw-Hill; 2006 .p. 488.
Complement deficiencies [Intenet]. 2011 [cited 2011 May 21]. Available from: http://www.wrongdiagnosis.com/l/leiner_disease/book-diseases-20a. htm
Collins CD, Hivnor C. Seborrheic dermatitis. In: Goldsmith LA, Katz SI, Gilchrest BA, Paller AS, Leffel DJ, Wolff K, eds. Fitzpatrick’s dermatology in general medicine. Vol 1. 8th ed. New York: McGrawHill; 2012 .p. 263
O’Toole MT. Mosby’s medical dictionary. 9th Ed. Canada: Mosby Elsevier; 2009.
Silverberg ND, McKinster CD, Tay YK. Pediatric skin of color. In: Teoh YL, Tay YK, eds. Seborrheic dermatitis in children. New York: Springer; 2015 .p. 287-92.
Kotrulja L, Susic SM, Husar K. Differential diagnosis of neonatal and infantile erythroderma. Acta Dermatovenerol Croat. 2007;15:178-90
Keane M, O’Toole MT. Encyclopedia and dictionary of medicine, nursing, and allied health. 7th ed. New Jersey: Saunders; 2005.
Rudikoff D. Infantile seborrheic dermatitis. In: Loden M, Maibach HI, eds. Dry skin and moisturizers. Boca Raton, Florida: CRC Press; 2000 .p. 157-64
Leiner disease [Internet]. 2011 [cited in 2016 Feb 2]. Available from: http://www.rightdiagnosis.com/l/leiner_disease/basics.htm
Erythroderma desquamativa of leiner [Internet]. 2016 [cited 2016 Feb 2]. Available from: https://rarediseases.info.nih.gov/gard/2191/erythrodermadesquamativa- of-leiner/resources/1#In%20Depth%20Information
Erythroderma desquamativa of Leiner [Internet]. 2010 [cited 2016 Feb 2]. Available from: http://www.orpha.net//consor/cgi-bin/OC_Exp. php?Lng=GB&Expert=314
Agrawal R, Jyonouchi H, Chilumkurti V, Windle ML, Steele RW. Complement deficiency epidemiology. Medscape [Internet]. 2015 [cited 2016 Feb 14]. Available from:http://emedicine.medscape.com/article/886 128-overview
Broberg A, Faergemann J. Infantile seborrheic dermatitis and Pityrosporum ovale. Br J Dermatol. 1989;120:359-62.
Ruiz-Maldonado R, Lopez-Matinez R, Chavarria EP, Castanon RL, Tamayo L. Pityrosporum ovale in infantile seborrheic dermatitis. Pediatr Dermatol. 1989;6:16-20.
Dhar S, Banerjee R, Malakar R. Neonatal erythroderma: Diagnostic and therapeutic challenges. Indian J Dermatol. 2012;57(6):475–8.
Schachner L, Hansen RC. Pediatric dermatology. Vol 1. 4th Ed. USA: Mosby Elsevier; 2011 .p. 445.
Sonea MJ, Moroz BE, Reece ER. Leiner’s disease associated with diminished third component of complement. Pediatr Dermatol. 1987;4(2):105-7.
Goodyear HM, Harper JI. Leiner’s disease associated with metabolic acidosis. Clin Exp Dermatol. 1989;14:364-6.
Schwartz RA, Chaganti RK. Complement deficiencies. Medscape [Internet]. 2015. Available from: http://emedicine.medscape.com/article/135478-overview
Arnaout R, Al Shorbaghi S, Al Dhekri H, Al-Mousa H, Al Ghonaium A, Al Saud B, et al. C5 complement deficiency in a Saudi family, molecular characterization of mutation and literature review. J Clin Immunol. 2013;33(4):871-5. doi: 10.1007/s10875-013-9872-7.
Sehgal VN, Srivastava G. Erythroderma/exfoliative dermatitis. In: Wolf R, Davidovici BB, Parish JL, Parish LC, eds. Emergency dermatology. Cambridge: Cambridge University Press; 2010 .p. 207
Nisenson A. Seborrheic dermatitis of infants and leiner’s disease: A biotin deficiency. J Pediatr. 1957; 51:537-48
Sanghvi SY, Schwartz RA. Leiner's disease (erythroderma desquamativum): A review and approach to therapy. Dermatol Ther. 2021;34(1):e14510.
World Health Organization. WHO child growth standard: Methods and development length/height for age, weight for length, weight for height, and body mass index for age. Geneva: World Health Organization; 2006.
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2023 Cermin Dunia Kedokteran
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
