Pengaruh Citicoline terhadap Tingkat Keparahan dan Status Fungsional Pasien Stroke Iskemik
Laporan Kasus Berbasis Bukti
DOI:
https://doi.org/10.55175/cdk.v51i4.1052Kata Kunci:
Citicoline, derajat keparahan, status fungsional, stroke iskemikAbstrak
Latar Belakang: Stroke merupakan penyebab mortalitas, morbiditas, dan disabilitas jangka panjang. Neuroprotektor, salah satunya citicoline, merupakan pilihan terapi pasien yang tidak mungkin diberi rTPA. Laporan kasus berbasis bukti ini bertujuan untuk melihat hubungan citicoline dengan tingkat keparahan dan status fungsional stroke iskemik. Metode: Penelusuran menggunakan database Scopus. Dari 191 studi yang diperoleh, terpilih 3 artikel untuk telaah kritis, yaitu Ghosh, et al, (2015), Martynov, et al, (2013), dan Mehta, et al, (2019). Hasil: Terdapat perbedaan signifikan status fungsional yang diukur dengan indeks Barthel dan modified Rankin Scale (mRS), dan keparahan stroke diukur dengan NIHSS. Pada pasien kami terjadi perbaikan indeks Barthel dan skor NIHSS yang bermakna pada hari ke-16. Simpulan: Citicoline berpengaruh signifikan terhadap status fungsional dan derajat keparahan stroke iskemik.
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Referensi
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