Perbandingan TIO Sebelum dan Sesudah Operasi pada Pasien Vitrektomi Berbantuan Triamsinolon dengan dan Tanpa Pembedahan Lensa
Hasil Penelitian
DOI:
https://doi.org/10.55175/cdk.v52i7.1592Kata Kunci:
Tekanan intraokular, triamcinolone, vitrektomi, operasi vitreoretinalAbstrak
Pendahuluan: Penelitian retrospektif ini mengevaluasi dampak vitrektomi berbantu triamcinolone terhadap tekanan intraokular (TIO) pasien yang menjalani operasi vitreoretina, membandingkan hasil pada pasien dengan dan tanpa operasi lensa. Metode: Rekam medis pasien di RSUP RD. Kandou dari Mei 2019 hingga Mei 2024 ditinjau; nilai TIO sebelum dan sesudah operasi dianalisis. Sebanyak 35 pasien memenuhi kriteria inklusi. Hasil: Hasil penelitian menunjukkan penurunan TIO yang signifikan pada semua interval pasca-operasi, dengan perbedaan rata-rata sebesar 11,12 mmHg pada hari pertama, 8,60 mmHg pada minggu pertama, 13,23 mmHg pada bulan pertama, dan 16,91 mmHg pada bulan pasca-operasi. Tidak ada perbedaan signifikan TIO antara pasien dengan lensa phakik dan pseudophakik. Simpulan: Temuan ini menunjukkan bahwa vitrektomi berbantu triamcinolone efektif menurunkan TIO, terlepas dari status lensa.
Unduhan
Referensi
Kampougeris G, Cheema R, McPherson R, Gorman C. Safety of triamcinolone acetonide (TA)-assisted pars plana vitrectomy in macular hole surgery. Eye. 2007;21(5):591-4. DOI: 10.1038/sj.eye.6702265.
Sakamoto T, Miyazaki M, Hisatomi T, Nakamura T, Ueno A, Itaya K, et al. Triamcinolone-assisted pars plana vitrectomy improves the surgical procedures and decreases the postoperative blood–ocular barrier breakdown. Graefe's Arch Clin Experiment Ophthalmol. 2002;240:423-9. DOI: 10.1007/s00417-002-0454-2.
Aceves-Franco LA, Sanchez-Aguilar OE, Barragan-Arias AR, Ponce-Gallegos MA, Navarro-Partida J, Santos A. The evolution of triamcinolone acetonide therapeutic use in retinal diseases: From off-label intravitreal injection to advanced nano-drug delivery systems. Biomedicines 2023;11(7):1901. DOI: 10.3390/biomedicines11071901.
Farah ME, Rodrigues EB, Maia A, Magalhaes JR O, Lima A. Vital dyes for staining intraocular membranes and tissues during citrectomy. Retina Today [Internet]. 2010 Jul-Aug;28-32. Available from: https://retinatoday.com/articles/2010-july-aug/vital-dyes-for-staining-intraocular-membranes-and-tissues-during-vitrectomy.
Sakamoto T, Ishibashi T. Visualizing vitreous in vitrectomy by triamcinolone. Graefe's Arch Clin Experiment Ophthalmol. 2009;247:1153-63. DOI: 10.1007/s00417-009-1118-2.
Park HY, Yi K, Kim HK. Intraocular pressure elevation after intravitreal triamcinolone acetonide injection. Korean J Ophthalmol. 2005;19(2):122-7. DOI: 10.3341/kjo.2005.19.2.122.
Kiddee W, Trope GE, Sheng L, Beltran-Agullo L, Smith M, Strungaru MH, et al. Intraocular pressure monitoring post intravitreal steroids: A systematic review. Survey Ophthalmol. 2013;58(4):291-310. DOI: 10.1016/j.survophthal.2012.08.003.
Wykrota AA, Abdin AD, Munteanu C, Low U, Seitz B. Incidence and treatment approach of intraocular pressure elevation after various types of local steroids for retinal diseases. Graefe's Arch Clin Experiment Ophthalmol. 2023;261(12):3569-79. DOI: 10.1007/s00417-023-06163-5.
Gillies MC, Simpson JM, Billson FA, Luo W, Penfold P, Chua W, et al. Safety of an intravitreal injection of triamcinolone: results from a randomized clinical trial. Arch Ophthalmol. 2004;122(3):336-40. DOI: 10.1001/archopht.122.3.336.
Jonas JB, Degenring RF, Kreissig I, Akkoyun I, Kamppeter BA. Intraocular pressure elevation after intravitreal triamcinolone acetonide injection. Ophthalmology 2005;112(4):593-8. DOI: 10.1016/j.ophtha.2004.10.042.
Parke III DW, Sisk RA, Houston SK, Murray TG. Ocular hypertension after intravitreal triamcinolone with vitrectomy and phacoemulsification. Clin Ophthalmol. 2012:925-31. DOI: 10.2147/OPTH.S32934.
Jonas JB. Intravitreal triamcinolone acetonide: A change in a paradigm. Ophthalmic Res. 2006;38(4):218-4510.1159/000093796. DOI: 10.1159/000093796.
Shrivastava A, Singh K. The impact of cataract surgery on glaucoma care. Curr Opin Ophthalmol. 2014;25(1):19-25. DOI: 10.1097/ICU.0000000000000010.
Allam G, Ellakkany R, Ellayeh A, Mohsen T, Abouelkheir HE, Gaafar W. Outcome of pediatric cataract surgery with intraocular injection of triamcinolone acetonide: Randomized controlled trial. Eur J Ophthalmol. 2018;28(6):633-8. DOI: 10.1177/1120672117754168.
Yamakiri K, Sakamoto T, Noda Y, Nakahara M, Ogino N, Kubota T, et al. One-year results of a multicenter controlled clinical trial of triamcinolone in pars plana vitrectomy. Graefe's Arch Clin Experiment Ophthalmol. 2008;246:959-66. DOI: 10.1007/s00417-008-0829-0.
Hollands H, Seif G, Hollands S, Gale J. A trial of topical prednisolone acetate before intravitreal triamcinolone acetonide decreases intraocular pressure spikes. Canad J Ophthalmol. 2010;45(5):484-8. DOI: 10.3129/i10-050.
Koval MS, Moster MR, Freidl KB, Waisbourd M, Jain SG, Ichhpujani P, et al. Intracameral triamcinolone acetonide in glaucoma surgery: A prospective randomized controlled trial. Am Jf Ophthalmol. 2014;158(2):395-401. e2. DOI: 10.1016/j.ajo.2014.04.027.
Slabaugh MA, Bojikian KD, Moore DB, Chen PP. Reply: Intraocular pressure spike prophylaxis in glaucoma patients 1 day after phacoemulsification. J Cataract Refractive Surg. 2014;40(6):1055-6. DOI: 10.1016/j.jcrs.2014.05.001.
Parekh A, Srivastava S, Bena J, Albini T, Nguyen QD, Goldstein DA. Risk factors associated with intraocular pressure in patients with uveitis treated with the fluocinolone acetonide implant. JAMA Ophthalmol. 2015;133(5):568-73. DOI: 10.1001/jamaophthalmol.2015.51.
Ren Y, Du S, Zheng D, Shi Y, Pan L, Yan H. Intraoperative intravitreal triamcinolone acetonide injection for prevention of postoperative inflammation and complications after phacoemulsification in patients with uveitic cataract. BMC Ophthalmol. 2021;21(1):245. DOI: 10.1186/s12886-021-02017-y.
Grzybowski A, Kanclerz P. Do we need day-1 postoperative follow-up after cataract surgery? Graefe's Arch Clin Experiment Ophthalmol. 2019;257:855-61. DOI: 10.1007/s00417-018-04210-0.
Baudouin C, Kolko M, Melik-Parsadaniantz S, Messmer EM. Inflammation in glaucoma: From the back to the front of the eye, and beyond. Progr Retinal Eye Res. 2021;83:100916. DOI: 10.1016/j.preteyeres.2020.100916.
Couch SM, Bakri SJ. Intravitreal triamcinolone for intraocular inflammation and associated macular edema. Clin Ophthalmol. 2009;3:41-7. DOI: 10.2147/opth.s4477.
Chieh JJ, Roth DB, Liu M, Belmont J, Nelson M, Regillo C, et al. Intravitreal triamcinolone acetonide for diabetic macular edema. Retina. 2005;25(7):828-34. DOI: 10.1097/00006982-200510000-00002.
Ricker LJ, Kessels AG, de Jager W, Hendrikse F, Kijlstra A, la Heij EC. Prediction of proliferative vitreoretinopathy after retinal detachment surgery: potential of biomarker profiling. Am J Ophthalmol. 2012;154(2):347-54. e2. DOI: 10.1016/j.ajo.2012.02.004.
Bonfiglio V, Reibaldi M, Fallico M, Russo A, Pizzo A, Fichera S, et al. Widening use of dexamethasone implant for the treatment of macular edema. Drug design, Development and Therapy 2017;11:2359-72. DOI: 10.2147/DDDT.S138922.
Lusthaus JA, McCluskey PJ, Martin KR. Intraocular pressure spikes following iStent inject and the relationship to aqueous outflow in open angle glaucoma. J Glaucoma. 2023;32(7):600-8. DOI: 10.1097/IJG.0000000000002195.
Byrne S, Ng J, Hildreth A, Danjoux JP, Steel DH. Refractive change following pseudophakic vitrectomy. BMC Ophthalmol. 2008;8:1-6. DOI: 10.1186/1471-2415-8-19.
Liao M, Huang Y, Wang J, Meng X, Liu Y, Yu J, et al. Long-term outcomes of administration of intravitreal triamcinolone acetonide after posterior vitreous detachment during pars plana vitrectomy for proliferative diabetic retinopathy. Br J Ophthalmol. 2023;107(4):560-410. DOI: 10.1136/bjophthalmol-2021-320332.
Kumagai K, Furukawa M, Ogino N, Larson E, Uemura A. Long-term outcomes of macular hole surgery with triamcinolone acetonide–assisted internal limiting membrane peeling. Retina 2007;27(9):1249-54. DOI: 10.1097/IAE.0b013e3180ed45cc.
Dada T, Dhawan M, Garg S, Nair S, Mandal S. Safety and efficacy of intraoperative intravitreal injection of triamcinolone acetonide injection after phacoemulsification in cases of uveitic cataract. J Cataract Refractive Surg. 2007;33(9):1613-810. DOI: 10.1016/j.jcrs.2007.04.029.
Jampol LM, Yannuzzi LA, Weinreb RN. Glaucoma and intravitreal steroids. Ophthalmology 2005;112(8):1325-610. DOI: 1016/j.ophtha.2005.03.008.
Wang B, Dong N, Xu B, Liu J, Xiao L. Efficacy and safety of intracameral triamcinolone acetonide to control postoperative inflammation after phacotrabeculectomy. J Cataract Refractive Surg. 2013;39(11):1691-710. DOI: 10.1016/j.jcrs.2013.04.042.
Dyer D, Callanan D, Bochow T, Abraham P, Lambert HM, Lee SY, et al. Clinical evaluation of the safety and efficacy of preservative-free triamcinolone (Tiresence® [Triamcinolone acetonide injetable suspension] 40 mg/ml) for visualization during pars plana vitrectomy. Retina. 2009;29(1):38-4510. DOI: 10.1097/IAE.0b013e318188c6e2.
Bonanomi MTBC, Susanna R. Intravitreal triamcinolone acetonide as adjunctive treatment for neovascular glaucoma. Clinics. 2005;60(4):347-50. DOI: 10.1590/S1807-59322005000400014.
Unduhan
Diterbitkan
Cara Mengutip
Terbitan
Bagian
Lisensi
Hak Cipta (c) 2025 Ade John Nursalim, Vera Sumual, Ardelia Emily Wulur
Artikel ini berlisensi Creative Commons Attribution-NonCommercial 4.0 International License.
