Immune Thrombocytopenia

Penulis

  • Sandy Wijaya Rumah Sakit Tk.IV Madiun, Kota Madiun, Jawa Timur

DOI:

https://doi.org/10.55175/cdk.v46i11.402

Kata Kunci:

Imun, ITP, trombositopenia

Abstrak

Immune thrombocytopenia (ITP) merupakan penyakit autoimun yang menyebabkan destruksi dan penurunan produksi trombosit. Gejala yang sering adalah perdarahan mukokutan serta penurunan jumlah trombosit hingga kurang dari 100.000/µL. Terapi terdiri dari beberapa lini sesuai keadaan klinis untuk memperbaiki kualitas hidup pasien.

Immune thrombocytopenia (ITP) is an autoimmune disease that causes destruction and decrease in platelet production. The most common symptom is mucocutaneous bleeding and platelet count decrease to less than 100,000/µL. Therapy consists of several modalities depending on clinical condition to improve quality of life.

Unduhan

Data unduhan belum tersedia.

Referensi

Neunert C, Lim W, Crowther M, Cohen A, Solberg Jr L, Crowther MA. The American Society of Hematology 2011 evidence-based practice guideline for immune thrombocytopenia. Blood. 2011;117:4190-207.

Kistanguri G, Mc Crae K. Immune thrombocytopenia. Hematol Oncol Clin North Am. 2013;3: 495-520.

Swinkels M, Rijkers M, Voorberg J, Vidarsson G, Leebeek F, Jansen A. Emerging concepts in immune thrombocytopenia. Frontiers in Immunology. 2018;9:880

Neunert C. Management of newly diagnosed immune thrombocytopenia: Can we change outcomes? Blood Advances. 2017;1(24):2295-301.

McCrae K. Immune thrombocytopenia: No longer 'idiopathic'. Cleve Clin J Med. 2011;78(6):358-73.

Michel M. Immune thrombocytopenic purpura: Epidemiology and implications for patients. Eur J Haematol Suppl. 2009;71:3-7.

Zufferey A, Kapur R, Semple JW. Pathogenesis and therapeutic mechanisms in immune thrombocytopenia (ITP). J Clin Med. 2017;6(2). pii: E16. doi: 10.3390/jcm6020016.

Neunert CE. Current management of immune thrombocytopenia. American Society of Hematology. 2013;2013:276-82.

Stasi R. How to approach thrombocytopenia. Am Soc of Hematol. 2012;2012(1): 191-7

Wei Y, Ji XB, Wang YW, Wang Jx, Yang EQ, Wang ZC, et al. High-dose dexamethasone vs prednisone for treatment of adult immune thrombocytopenia: A prospective multicenter randomized trial. Blood. 2016; 127(3):296-302; quiz 370.

Bohn JP, Steurer M. Current and evolving treatment strategies in adult immune thrombocytopenia. memo. 2018;11:241-6

Roorprai JK, Khamisa K. Is there a role for biweekly romiplostim in the management of chronic immune thrombocytopenia (ITP)? A report of three cases. Case Rep Hematol. 2018;2018:6037494.

George JN. Sequence of treatments for adults with primary immune thrombocytopenia. Am J Hematol. 2012;20(87):12-15

Eghbali A, Azadmanesh P, Bagheri B, Taherahmadi H, Sadeghi Sedeh B. Comparison between IV immune globulin (IVIG) and anti-D globulin for treatment of immune thrombocytopenia: A randomized open-label study. Fundamental Clin Pharmacol. 2016;30(4):385-9.

Diterbitkan

2019-11-01

Cara Mengutip

Wijaya, S. (2019). Immune Thrombocytopenia. Cermin Dunia Kedokteran, 46(11), 658–661. https://doi.org/10.55175/cdk.v46i11.402

Terbitan

Bagian

Articles