Manajemen Varisela Neonatal
DOI:
https://doi.org/10.55175/cdk.v46i11.405Kata Kunci:
Asiklovir, varisela naonatal, varicella zoster virusAbstrak
Infeksi primer varicella-zoster virus (VZV) neonatal sangat menular dan berisiko tinggi menyebabkan kematian. Diagnosis klinis varisela neonatal melalui temuan lesi patognomonik dalam berbagai stadia di saat bersamaan. Infeksi ini dapat diatasi dengan terapi asiklovir; penelitian terbaru lebih merekomendasikan rute intravena dibandingkan rute oral, terutama untuk infeksi yang telah menyebar. Selain pengobatan, dilakukan pencegahan untuk meminimalkan penularan virus.
Primary infections of varicella-zoster virus (VZV) in neonatus are highly contagious and have a high risk of death. Neonatal varicella can be diagnosed clinically through simultanous pathognomonic lesions at various stages. Recent research shows that intravenous route is recommended, especially in systemic infections. Preventive measures should be taken to minimize virus transmission.
Unduhan
Referensi
Singh SN, Tahazzul M, Singh A, Chandra S. Varicella infection in a neonate with subsequent staphylococcal scalded skin syndrome and fatal shock. BMJ Case Rep. 2012;2012. pii: bcr2012006462.
Khandaker G, Marshall H, Peadon E, Zurynski Y, Burgner D, Buttery J, et al. Congenital and neonatal varicella: Impact of the national varicella vaccination programme in Australia. Arch Dis Childhood 2011;96(5):453-6
Sondakh C, Kandou RT, Kapantow GM. Profil varisela di poliklinik kulit dan kelamin RSUP Prof DR. RD Kandou Manado Periode Januari–Desember 2012. e-CliniC 2015; 3.1
van Lier A, van der Maas NA, Rodenburg GD, Sanders EA, de Melker HE. Hospitalization due to varicella in the Netherlands. BMC Infect Dis 2011;11(1): 85.
Varisela. In: Soedarmo SSP, Garna H, Hadinegoro SRS, Satari HI, editors. Buku ajar infeksi & pediatri tropis. Edisi ke-2. Jakarta: Badan Penerbit IDAI; 2008.
Chiriac A, et al. Perinatal varicella. Our Dermatology Online 2016;7(1):121-2
Lécuyer A, Levy C, Gaudelus J, Floret D, Soubeyrand B, Caulin E, et al. Hospitalization of newborns and young infants for chickenpox in France. Eur J Pediatr. 2010;169(10):1293-7
van den Berg JP, Westerbeek EA, Smits GP, van der Klis FR, Berbers GA, van Elburg RM. Lower transplacental antibody transport for measles, mumps, rubella and varicella zoster in very preterm infants. PLoS One 2014;9(4):94714.
Paller AS, Mancini AJ. Hurwitz clinical pediatric dermatology e-book: A textbook of skin disorders of childhood and adolescence. Elsevier Health Sciences’ 2015.
Ravikumar C. Varicella in the peripartum period. Neonatal infections. Springer, Cham; 2018 .p. 201-6.
Wolff K, Goldsmith L, Katz S, Gilchrest B, Paller AS, Leffell D. Fitzpatrick's dermatology in general medicine. 8th Edition. New York: McGraw-Hill; 2011.
Harbecke R, Oxman MN, Arnold BA, Ip C, Johnson GR, Levin MJ, et al. A real-time PCR assay to identify and discriminate among wild-type and vaccine strains of varicella-zoster virus and herpes simplex virus in clinical specimens, and comparison with the clinical diagnoses. J Med Virol. 2009;81(7):1310-22
Ozcan A, Senol M, Saglam H, Seyhan M, Durmaz R, Aktas E, et al. Comparison of the Tzanck test and polymerase chain reaction in the diagnosis of cutaneous herpes simplex and varicella zoster virus infections. Internat J Dermatol. 2007;46 (11):1177-9.
Pacifici GM. The Effects and pharmacokinetics of acyclovir in neonates. Internat J Pediatrics 2016;4(12):4099-115
Kimberlin DW. Acyclovir dosing in the neonatal period and beyond. J Pediatr Infect Dis Soc. 2013;2(2):179-82
Hey E, ed. Neonatal formulary: Drug use in pregnancy and the first year of life. John Wiley & Sons; 2011.
Tod M, Lokiec F, Bidault R, De Bony F, Petitjean O, Aujard Y. Pharmacokinetics of oral acyclovir in neonates and in infants: A population analysis. Antimicrob Agents Chemother. 2001;45(1):150-7
Chiodo F, Manfredi R, Antonelli P, Caramia G, Carnelli V, Catania S, et al. Varicella in immunocompetent children in the first two years of life: role of treatment with oral acyclovir. J Chemother. 1995;7(1):62-6
Kempf W, Meylan P, Gerber S, Aebi C, Agosti R, Büchner S, et al. Swiss recommendations for the management of varicella zoster virus infections. Swiss Med Weekly 2007;137(17/18):239
Bulakbasi N, Kocaoglu M. Central nervous system infections of herpesvirus family. Neuroimaging Clin North Am. 2008;18(1):53-84
Gershon AA, Silverstein SJ. Varicella-zoster virus. Clinical virology, 3rd Ed. American Society of Microbiology; 2009 .p. 451-73.
Nurputra DK, Rahmawati AS, Indrawanti R, Widjajanto PH, Arguni E, Safitri I, et al. Case series: Varicella-zoster in patients with acute lymphoblastic leukemia. Lesson Learned from Managing Outbreak in Resource Limited Facility. J Cancer Prev Curr Res [Internet]. 2018. Available from: https://pdfs.semanticscholar.org/dd9d/a45730c6ce898d6735c4e9fb202cf3785205.pdf
Miller E, Cradock-Watson TE, Ridehalgh MKS. Outcome in newborn babies given anti-varicella-zoster immunoglobulin after perinatal maternal infection with varicella-zoster virus. Lancet 1990;334(8659):371-3
Unduhan
Diterbitkan
Cara Mengutip
Terbitan
Bagian
Lisensi
Hak Cipta (c) 2019 https://creativecommons.org/licenses/by-nc/4.0/
Artikel ini berlisensi Creative Commons Attribution-NonCommercial 4.0 International License.
