The Role of Vitamin D in Enhancing Immunity and Its Recommendations

Penulis

  • Adianto Jaya Nagara Brawijaya University, Faculty of Medicine, Malang, Indonesia
  • Andry Gonius Brawijaya University, Faculty of Medicine, Malang, Indonesia

DOI:

https://doi.org/10.55175/cdk.v48i2.42

Kata Kunci:

Immunity, vitamin D

Abstrak

Vitamin D is a fat-soluble vitamin with a very important role in regulating the body’s calcium balance. It also plays an important role in cell growth, even optimizing the immune system. American Academy of Dermatology recommends supplementation of oral vitamin D to meet daily vitamin D requirements.

Vitamin D adalah vitamin larut dalam lemak yang penting untuk mengatur kadar kalsium tubuh, juga berperan dalam pertumbuhan sel dan sistem imun. Untuk memenuhi kebutuhan vitamin D dalam tubuh, American Academy of Dermatology menganjurkan suplementasi oral vitamin D.

Unduhan

Data unduhan belum tersedia.

Referensi

Laird E, Rhodes J, Kenny RA. Vitamin D and inflammation: Potential implications for severity of Covid-19. Issue: Ir Med J. 2020;113(5):81.

Marwah A, Marwah P. Coronavirus (COVID-19): A protocol for prevention, treatment and control. J App Nat Sci. 2020;12(2):119-23

Sizar O, Khare S, Goyal A, Bansal P, Givler A. Vitamin D deficiency. NCBI [Internet]. 2020. Available from: https://www.ncbi.nlm.nih.gov/books/NBK532266/

Alipio M. Vitamin D supplementation could possibly improve clinical outcomes of patients infected with Coronavirus-2019 (COVID2019). Department of Radiologic Technology College of Allied Health Sciences Davao Doctors College Gen. Malvar St., Davao City 8000 Davao del Sur, Philippines; 2020.

Palacios C, Gonzales L. Is vitamin D deficiency a major global public health problem? Nutrition Program, School of Public Health, Medical Sciences Campus,University of Puerto Rico. J Steroid BiochemMol Biol. 2014;144PA:138–45. doi:10.1016/j.jsbmb.2013.11.003.

Holick MF. The vitamin D epidemic and its health consequences. J Nutr. 2005; 135(11):2739-48. doi:10.1093/jn/135.11.2739S.

Nair R, Maseeh A. 2012. Vitamin D: The “sunshine” vitamin. J Pharmacol Pharmacother 2012;3:118-26

Gill A, Plaza-Diaz J, Mesa MD. Vitamin D: Classic and novel actions. Ann Nutr Metab. 2018;72:87-95. doi: 10.1159/000486536.

Biesalski HK. Vitamin D deficiency and co-morbidities in COVID-19 patients – A fatal relationship? NFS Journal. 2020;20:10-21.

McGonagle D, Sharif K, O’Regan A, Bridgewood C. The role of cytokines including interleukin-6 in COVID-19 induced pneumonia and macrophage activation syndrome-like disease. Autoimmun Rev. 2020;19(6):102537. doi:10.1016/j.autrev.2020.102537.

Yang I, Xu J, Zhang H. Effects of vitamin D on ACE2 and vitamin D receptor expression in rats with LPS induced acute lung injury. Chin J Em Med. 2016;25:1284–9.

Daneshkhah A, Agrawal V, Esheim A, Subramanian H, Roy HK, Backman V. The possible role of vitamin D in suppressing cytokine storm and associated mortality in COVID-19 patients [Internet]. 2020. Available from: https://www.medrxiv.org/content/10.1101/2020.04.08.20058578v4.full.pdf+html

Badan Meteorologi dan Geofisika (BMKG). Indeks Sinar Ultraviolet (UV) [Internet]. 2020 [cited 2020 Jul 17]. Available from: https://www.bmkg.go.id/cuaca/indeks-uv.bmkg.

Young C. Solar ultraviolet radiation and skin cancer. Occupational Medicine 2009;59:82–88. doi:10.1093/occmed/kqn170.

Svobodová A,Vostálová J. Solar radiation induced skin damage: Review of protective and preventive options. Internat J Rad Biol. 2010;86:999-1030.10.3109/09553002.2010.501842.

Gilchrest BA. Sun exposure and vitamin D sufficiency. Am J Clin Nutr 2008;88(suppl):570–7.

Melnikova VO, Ananthaswamy HN. Cellular and molecular events leading to the development of skin cancer. Mutat Res. 2005; 571(1-2):91-106.

American Academy of Dermatology (AAD). Vitamin D [Internet]. 2020 [cited 2020 Jul 17]. Available from: https://www.aad.org/media/stats-vitamin-d.

Ministry of Health and Cancer Society of New Zealand. 2012. Consensus Statement on Vitamin D and Sun Exposure in New Zealand. Wellington: Ministry of Health. Published in March 2012 by the Ministry of Health, PO Box 5013, Wellington 6145, New Zealand.

Diterbitkan

2021-02-01

Cara Mengutip

Jaya Nagara, A., & Gonius, A. (2021). The Role of Vitamin D in Enhancing Immunity and Its Recommendations. Cermin Dunia Kedokteran, 48(2), 99–102. https://doi.org/10.55175/cdk.v48i2.42