Suplementasi Vitamin D pada Tatalaksana Obesitas

Penulis

  • Putri Sakti Dwi Permanasari Rumah Sakit Permata Cibubur, Rumah Sakit Permata Jonggol, Jakarta Life Science and Aesthetic Clinic, Indonesia

DOI:

https://doi.org/10.55175/cdk.v48i2.43

Kata Kunci:

massa lemak, obesitas, vitamin D

Abstrak

Kadar vitamin D serum memiliki korelasi terbalik dengan massa jaringan adiposa; makin tinggi IMT dan massa lemak tubuh seseorang, kadar vitamin D serumnya makin rendah. Sebaliknya defisiensi vitamin D dapat menurunkan respons terapi penurunan berat badan. Suplementasi vitamin D pada terapi obesitas perlu dipertimbangkan untuk menjaga kadar vitamin D serum tetap optimal, sehingga terapi penurunan berat badan dapat optimal. Beberapa rekomendasi organisasi berdasarkan pertimbangan para ahli dapat menjadi acuan pemberian suplementasi vitamin D pada kondisi obesitas.

Serum vitamin D levels have an inverse correlation with adipose tissue mass; the higher a person’s BMI and body fat mass, the lower serum vitamin D level. Conversely, vitamin D deficiency can reduce the response to weight loss therapy. Vitamin D supplementation in obesity therapy needs to be considered to maintain optimal serum vitamin D levels in order to more effective weight loss therapy. Recommendations from several organizations based on expert considerations can be used as a reference for vitamin D supplementation in obese conditions

Unduhan

Data unduhan belum tersedia.

Referensi

Baldwin L. Obesity: Understanding, awareness and sensitivity. Dorland Health [Internet]. Available from: http://www.dorlandhealth.com/dorland-health-articles/obesity-understandingawareness-and-sensitivity

WHO/IASO/IOTF. The Asia-Pacific perspective: Redefining obesity and its treatment. Health communication Australia. Melbourne; 2000.

World Health Organization. Fact sheets no 311, obesity and overweight [Internet]. 2015 [cited 2016 March 4]. Available from: http://www.who.int/mediacentre/factsheets/fs311/en

Grooper SS, Smith JL, Groof JL. Body composition, energy expenditure, and energy balance. Advanced nutrition and human metabolism. 5th ed. Canada: Wadsworth, Cengage Learning; 2009 .p. 279-302.

Wortsman J, Matsuoka L, Chen T, Lu Z, Holick M. Decreased bioavailability of vitamin D in obesity. The American Journal of Clinical Nutrition 2000;72:690-3.

Yao Y, Zhu L, He L, Duan Y, Liang W, Nie Z, et al. A meta-analysis of the relationship between vitamin D deficiency and obesity. Int J Clin Exp Med. 2015;8(9):14977–84.61.

Tamer G, Mesci B, Tamer I, Kilic D, Arik S. Is vitamin D deficiency an independent risk factor for obesity and abdominal obesity in women? Endokrynol Pol.2012;63(3):196–201.

Nair R, Maseeh A. Vitamin D: The "sunshine" vitamin. J Pharmacol Pharmacother. 2012;3(2):118-26.

Vera, Setiati S, Govinda A. Determinan diagnosis klinis defisiensi vitamin D pada wanita berusia lebih dari 50 tahun. Jurnal Penyakit Dalam Indonesia. 2015;1:38-48.

Pereira-Santos M, Costa PR, Assis AM, Santos CA, Santos DB. Obesity and vitamin D deficiency: A systematic review and meta-analysis. Obes Rev. 2015;16(4):341-9

Holick MF. Vitamin D deficiency. New England Journal of Medicine 2007;357(3):266-81.

Your guide to understanding vitamin D [Internet]. Available from: https://vitamindwiki.com/Your+guide+to+understanding+vitamin+D+%E2%80%93+Vitamin+D+Council+Dec+2013

Gallangher ML. The nutrient and their metabolism. In: Mahan LK, Escott-stump S, editors. Krause’s food and nutritition therapy. 12th Ed. Canada: Saunders Elsevier; 2008.

Combs Jr. GF. The vitamins fundamental aspects in nutrition and health. 3rd Ed. USA: Elsevier; 2008.

Bender DA. Vitamin D. In: Bender DA, editor. Nutritional biochemistry of the vitamins. 2nd Ed. UK: Cambridge University Press; 2003 .p. 77-90.

Rodríguez-Rodríguez E, Navia B, López-Sobaler AM, Ortega RM. Vitamin D in overweight/obese women and its relationship with dietetic and anthropometric variables. Obes Silver Spring Md. 2009;17(4):778–82

Khor GL, Chee WS, Shariff ZM, Poh BK, Arumugam M, Rahman JA, et al. High prevalence of vitamin D insufficiency and its association with BMI-for-age among primary school children in Kuala Lumpur, Malaysia. BMC Public Health. 2011;11:95.

Ekwaru JP, Zwicker JD, Holick MF, Giovannucci E, Veugelers PJ. The importance of body weight for the dose response relationship of oral vitamin D supplementation and serum 25-hydroxyvitamin D in healthy volunteers. PLoS ONE 2014;9(11):e111265.

Gallagher JC, Peacock M, Yalamanchili V, Smith LM. Effects of vitamin D supplementation in older African American women. J Clin Endocrinol Metab. 2013;3:1137-46

Wortsman J, Matsuoka LY, Chen TC, Lu Z, Holick MF. Decreased bioavailability of vitamin D in obesity. Am J Clin Nutr. 2000;72(3):690-3.

Bonnet L, Margier M, Svilar L, Couturier C, Reboul E, Martin J, et al. Simple fast quantification of cholecalciferol, 25-hydroxyvitamin D and 1,25-dihydroxyvitamin D in adipose tissue using LC-HRMS/MS. Nutrients 2019;11:1977.

Blum M, Dolnikowski G, Seyoum E, Harris SS, Booth SL, Peterson J, et al. Vitamin D(3) in fat tissue. Endocrine 2008;33(1):90-4.

Li J, Byrne ME, Chang E, Jiang Y, Donkin SS, Buhman KK, et al. 1 alpha,25-DiOH D hydroxylase in adipocytes. J Steroid Biochem Mol Biol. 2008;112(1-3):122-6

Hewison M. Vitamin D dan the immune system: New perspectives on an old theme. Endocrinol Metab Clin North Am. 2010;39(2):365-79.

Harford KA, Reynolds CM, McGillicuddy FC, Roche HM. Fats, inflammation daninsulin resistance: insights to the role of macrophage dan T-cell accumulation in adipose tissue. Proc Nutr Soc. 2011;70(4):408-17

Christakos S, Ajibade DV, Dhawan P, Fechner AJ, Mady LJ. Vitamin D: Metabolism. Endocrinol Metab Clin North Am. 2010;39(2):243-53.

Christakos S, Hewison M, Gardner DG, Wagner CL, Sergeev IN, Rutten E, et al. Vitamin D: Beyond bone. Ann N Y Acad Sci. May ;1287:45-58.consequences. Am J Clin Nutr. 2013;87(4):1080S1086S.

Wortsman J, Matsuoka LY, Chen TC, Lu Z, Holick MF. Decreased bioavailability of vitamin D in obesity. Am J Clin Nutr. 2000;72(3):690–3.

Yao Y, Zhu L, He L, Duan Y, Liang W, Nie Z, et al. A meta-analysis of the relationship between vitamin D deficiency and obesity. Int J Clin Exp Med. 2015;8(9):14977–84

Tamer G, Mesci B, Tamer I, Kilic D, Arik S. Is vitamin D deficiency an independent risk factor for obesity and abdominal obesity in women? Endokrynol Pol. 2012;63(3):196–201.

Rogge MM. The role of impaired mitochondrial lipid oxidation in obesity. Biol Res Nurs. 2009;10(4):356–73

Greenberg AS, Obin MS. Obesity and the role of adipose tissue in inflammation and metabolism. Am J Clin Nutr. 2006;83(2):461–5

Singla P, Bardoloi A, Parkash AA. Metabolic effects of obesity: A review. World J Diabetes. 2010;1(3):76–88.

Szymczak-Pajor I, Śliwińska A. Analysis of association between vitamin D deficiency and insulin resistance. Nutrients 2019;11:794.

Pittas AG, Lau J, Hu F, Dawson-Hughes B. The role of vitamin D and calcium in type 2 diabetes. A systematic review and meta-analysis. J Clin Endocrinol Metab. 2007;92(6):2017–29.

Al-Shoumer KA, Al-Essa TM. Is there a relationship between vitamin D with insulin resistance and diabetes mellitus? World J Diabetes. 2015;6(8):1057– 64.

Attie AD, Scherer PE. Adipocyte metabolism and obesity. J Lipid Res. 2009; 50 Suppl:395-9.

Dawson-Hughes B, Mithal A, Bonjour JP, Boonen S, Burckhardt P, El-Hajj Fuleihan G, et al. IOF position statement: vitamin D recommendations for older adults. Osteoporos Int 2010;21(7):1151–4

Holick MF, Binkley NC, Bischoff-Ferrari HA, Gordon CM, Hanley DA, Heaney RP, et al. Evaluation, treatment, and prevention of vitamin D deficiency: an Endocrine Society clinical practice guideline. J Clin Endocrinol Metab 2011;96(7):1911–30

Pludowski P, Karczmarewicz E, Bayer M, Carter G, Chlebna-Sokol D, CzechKowalska J, et al. Practical guidelines for the supplementation of vitamin D and the treatment of deficits in Central Europe - recommended vitamin D intakes in the general population and groups at risk of vitamin D deficiency. Endokrynol Pol 2013;64(4):319–27

Recommendations abstracted from the American Geriatrics Society consensus statement on vitamin D for prevention of falls and their consequences. J Am Geriatr Soc 2014;62(1):147–52.

Diterbitkan

2021-02-01

Cara Mengutip

Dwi Permanasari, P. S. (2021). Suplementasi Vitamin D pada Tatalaksana Obesitas. Cermin Dunia Kedokteran, 48(2), 104–107. https://doi.org/10.55175/cdk.v48i2.43