Respons Sistem Imun pada Epilepsi

Penulis

  • Komang Juwita Endrawati RSU Dharma Yadnya, Denpasar, Bali, Indonesia

DOI:

https://doi.org/10.55175/cdk.v45i11.692

Kata Kunci:

Epilepsi, sistem imun

Abstrak

Epilepsi merupakan kondisi kronis dengan penyebab multifaktorial. Jumlah pasien resisten obat sekitar 20-40% diduga akibat keterlibatan peran imun dalam epileptogenesis. Beberapa komponen imunitas neuron berperan pada patogenesis epilepsi dan penggunaan obat anti epilepsi berpengaruh pada sistem imun. Obat anti epilepsi bersifat imunosupresan; imunitas innate dan adaptif berubah bermakna saat dan setelah kejang.

Epilepsy is a chronic condition with multifactorial causes. Aproximately 20-40% patients are drug resistant thought to be due to role of immunity in epileptogenesis. Some components of immunity in neurons play a role in the pathogenesis of epilepsy. Anti-epilepsy drugs are immunosuppressive; innate; adaptive immunity changes significantly during and after seizures.

Unduhan

Data unduhan belum tersedia.

Referensi

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Diterbitkan

2018-11-01

Cara Mengutip

Endrawati, K. J. (2018). Respons Sistem Imun pada Epilepsi. Cermin Dunia Kedokteran, 45(11), 815–818. https://doi.org/10.55175/cdk.v45i11.692

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