Angina Prinzmetal - Diagnosis dan Tatalaksana

Penulis

  • Tommy RSUD Zainal Umar Sidiki, Gorontalo Utara, Indonesia

DOI:

https://doi.org/10.55175/cdk.v48i6.79

Kata Kunci:

tatalaksana, pendekatan diagnosis, Angina Prinzmetal

Abstrak

Angina Prinzmetal merupakan sindrom klinis yang dicirikan dengan nyeri dada saat istirahat disertai perubahan elektrokardiogram sementara. Insidens lebih tinggi pada populasi Asia dengan rentang usia di atas 50 tahun. Merokok dan penggunaan obat-obatan tertentu dapat meningkatkan risiko angina Prinzmetal. Penyakit ini jarang terdiagnosis sehingga tatalaksananya belum optimal. Diagnosis berdasarkan kriteria Coronary Vasomotion Disorders International Study Group dan pemeriksaan penunjang seperti elektrokardiografi, uji provokatif, atau pencitraan intrakoroner. Tatalaksana mencakup perubahan gaya hidup, terapi farmaka, atau intervensi koroner perkutan. Prognosis mengacu pada hasil skor risiko Japanese Coronary Spasm Association, umumnya baik.

Prinzmetal’s angina is a clinical syndrome in which angina occurs at rest with transient electrocardiogram changes. The incidence is higher in the Asian population with age ranges above 50 years. Smoking and use of certain drugs can increase the risk of Prinzmetal’s angina. This disease is underdiagnosed so that the treatment is not optimal. Diagnosis is made based on the Coronary Vasomotion Disorders International Study Group Criteria and workups examinations such as electrocardiography, provocative test, or intracoronary imaging. The management includes lifestyle changes, pharmacotherapy, or percutaneous coronary intervention. Prognosis refers to the Japanese Coronary Spasm Association risk score, is generally good.

Unduhan

Data unduhan belum tersedia.

Referensi

Braunwald E, Mann, DL, Zipes DP, Libby P, Bonow RO. Braunwald’s Heart Disease: A Textbook of Cardiovascular Medicine. 10th ed. Philadelphia: Elsevier; 2015. p.1172-3.

Picard F, Sayah N, Spagnoli V, Adjedj J, Varenne O. Vasospastic angina: A literature review of current evidence. Arch Cardiovasc Dis. 2019;112(1):44-55.

Ziccardi MR, Hatcher JD. Prinzmetal angina. In: StatPearls [Internet]. 2019 [cited 2020 Apr 6]. Available from: https://www.ncbi.nlm.nih.gov/books/NBK430776/

JCS Joint Working Group. Guidelines for diagnosis and treatment of patients with vasospastic angina (Coronary Spastic Angina) (JCS 2013). Circ J. 2014; 78:2779-801.

Kabo P. Bagaimana menggunakan obat-obat kardiovaskular secara rasional.1st ed. Jakarta: Badan Penerbit FKUI; 2010. p. 137-8.

Cho SW, Park TK, Gwag HB, Lim AY, Oh MS, Lee DH, et al. Clinical outcomes of vasospastic angina patients presenting with acute coronary syndrome. J Am Heart Assoc 2016;5(11):e004336.

Beltrame JF, Crea F, Kaski JC, Ogawa H, Ong P, Sechtem U, et al. International standardization of diagnostic criteria for vasospastic angina. Eur Heart J. 2017;38:2565-8.

Beltrame JF. Variant angina. E-Journal of Cardiology Practice [Internet]. 2013 [cited 2020 Apr 5]. Available from: https://www.escardio.org/Journals/E-Journal-of-Cardiology-Practice/Volume-11/Variant-Angina

Goldberger AL, Goldberger ZD, Shvilkin A. Goldberger’s clinical electrocardiography: A simplified approach. 8th ed. Philadelphia: Elsevier; 2013. p. 87-8.

Roffi M, Patrono C, Collet JP, Mueller C, Valgimigli M, Andreotti F, et al. 2015 ESC Guidelines for the management of acute coronary syndromes in patients presenting without persistent ST-segment elevation: Task force for the management of acute coronary syndromes in patients presenting without persistent ST-segment elevation of the European Society of Cardiology (ESC). Eur Heart J. 2016;37:267-315.

Yasue H, Mizuno Y, Harada E, Itoh T, Nakagawa H, Nakayama M, et al. Effects of a 3-hydroxy-3-methylglutaryl coenzyme a reductase inhibitor, fluvastatin, on coronary spasm after withdrawal of calcium-channel blockers. J Am Coll Cardiol. 2008;51:1742-8.

Takagi Y, Takahashi J, Yasuda S, Miyata S, Tsunoda R, Ogata Y, et al. Prognostic stratification of patients with vasospastic angina: A comprehensive clinical risk score developed by the Japanese Coronary Spasm Association. J Am Coll Cardiol. 2013; 62(13):1144-53.

Diterbitkan

2021-06-02

Cara Mengutip

Tommy. (2021). Angina Prinzmetal - Diagnosis dan Tatalaksana. Cermin Dunia Kedokteran, 48(6), 315–318. https://doi.org/10.55175/cdk.v48i6.79

Terbitan

Bagian

Articles